Ischemic enterocolitis and its differential diagnosis
Abstract
Ischemia is a common type of gastrointestinal injury that can be clinically misdiagnosed due to its often mild and transient clinical presentation as well as a tendency to masquerade as other disorders. A wide range of etiologies can contribute to the development of ischemia. These include hypovolemic states, systemic diseases such as vasculitis and hypercoagulable states, mechanical obstruction, therapeutic drug effects, infection, and a host of other diseases. An accurate diagnosis of ischemia relies on a strong clinical suspicion in combination with endoscopic and pathologic findings. Most cases show histologic features that are diagnostic of ischemia, but do not point to a specific differential diagnosis, whereas the cause of ischemia can be recognized or suspected based on careful review of vascular changes in others. This review is focused on providing an overview of ischemic enterocolitis and its differential diagnosis.
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Enterocolonic ischemia may be due to systemic or infectious vasculitis, fibromuscular dysplasia, radiation and amyloidosis.
“Enterocolonic ischemia may also be due to systemic or infectious vasculitis, fibromuscular dysplasia, radiation and amyloidosis[9].”
From Ischemic bowel disease in 2021. (2021) · cites this paper as [9]
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References 72 · Cited by 18
- Authors
- Uberti, G., Goldblum, J. R., & Allende, D. S.
- Affiliations
- Cleveland Clinic (US)
- Corresponding author
- Allende, Daniela S.
- Venue
- Seminars in Diagnostic Pathology
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 31
- Issue
- 2
- Pages
- 152-164
- ISSN
- 0740-2570 (ISSN-L)
- OpenAlex
- W2017945584
- Cited by
- 18
- References
- 72
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 1 · 2019: 1 · 2018: 1 · 2016: 1
- FWCI
- 0.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Diagnostic Pathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Abdominal vascular conditions and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Gastrointestinal disorders and treatments
- Keywords
- intestinal ischemia, differential diagnosis, vasculitis, hypercoagulability, mechanical intestinal obstruction, drug-induced intestinal injury, endoscopic findings, vascular changes
- MeSH terms
- Colon, Diagnosis, Differential, Enterocolitis, Humans, Intestine, Small, Ischemia, Vasculitis, Endoscopy, Gastrointestinal
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