Synthesis of Peptides and Peptidomimetics

Abstract

It is now over 100 years since the first report of peptide synthesis by Emil Fischer in 1899. Houben-Weyl Synthesis of Peptides and Peptidomimetics, published in the English language, will reflect the current changes of this important discipline, which is at the center of modern chemistry and biology. The four-volume set, edited by the internationally renowned peptide chemists Professors Murray Goodman, Arthur Felix, Luis Moroder, and Claudio Toniolo will comprise a critical selection of synthetic methods in a consistent style. Synthesis of Peptides includes protecting groups, peptide bond formation, the synthesis of peptides and proteins detailing general and specific methods, and analytical techniques used to determine the structure and composition of peptides. Synthesis of Peptidomimetics features side and/or main chain modified peptides, peptides with secondary structure mimetics and inducers, de novo peptide structures, macropeptide structures and reactive peptides. Synthesis of Peptides and Peptidomimetics will be indispensable for every synthetic chemist.