NEMA NU 2-2018 performance measurements of Biograph Vision Quadra PET/CT system

Abstract

Ziel/Aim We evaluated the Biograph Vision Quadra (Siemens Healthineers) total-body PET/CT system according to the NEMA NU2-2018 standard for comparison with other PET/CT systems. The new PET/CT system builds on the technology of the SiPM-based Biograph Vision 600 (Siemens Healthineers) and has an axial field of view (AFOV) of 106 cm. This setup offers full coverage of a human torso together with a much higher imaging sensitivity. Methodik/Methods Spatial resolution was measured with a Na-22 point source. Scatter fraction, noise equivalent count rate (NECR), sensitivity, correction accuracies, CT co-registration accuracy, image quality and time-of flight (TOF) resolution were measured with F-18 sources. Two image quality measurements were performed with foreground to background ratios of 4 to 1 and 8 to 1, both with TOF and PSF reconstruction (TrueX TOF). Image reconstruction used a maximum ring difference (MRD) of 85. For all other measurements, MRDs of 85 and 322 were used. Ergebnisse/Results The radial, tangential and axial spatial resolutions were 3.3, 3.4 and 3.8 mm, as measured with MRD 85. Sensitivities in MRD 85 and MRD 322 modes were 83.4 cps/kBq and 176.0 cps/kBq, and the NECRs at peak were 1.641 kcps and 3.018 kcps, both at 28.3 kBq/ml. Scatter fraction at peak NECR was 36.5 % and 37.0 %, respectively. The TOF resolution was 225 ps for MRD 85 and 227 ps for MRD 322. Image contrast recovery was between 74.4 to 86.9 % for 4:1 and between 77.6 to 92.6 % for 8:1 contras…