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An Improved One-pot Procedure for the Synthesis of Alkynes from Aldehydes
Abstract
All articles of this category The transformation of aldehydes to terminal alkynes can be achieved with the reagent dimethyl-1-diazo-2-oxopropylphosphonate 2 . The one-pot procedure allows the isolation of the products under very mild conditions in good to excellent yields without requiring low temperatures or inert gas techniques and avoiding the use of strong bases. aldehydes - alkynes - dimethyl-1-diazo-2-oxopropylphosphonate
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Cited by
Palladium‐Catalyzed Cross‐Coupling Reactions in Total Synthesis
Nicolaou, K. C., Bulger, P. G., & Sarlah, D. (2005) · Angewandte Chemie International Edition · doi:10.1002/anie.200500368 · Cited by 2,708
Link, J. O., Taylor, J. G., Xu, L., Mitchell, M., Guo, H., Liu, H., Kato, D., Kirschberg, T., Sun, J., Squires, N., et al. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm401499g · Cited by 295
Ferreira, I., Falcato, F., Bandarra, N., & Rauter, A. P. (2022) · Molecules · doi:10.3390/molecules27051677 · Cited by 120
Metadata
- Authors
- Müller, S., Liepold, B., Roth, G. J., & Bestmann, H. J.
- Venue
- Synlett
- Publisher
- Georg Thieme Verlag KG
- Published
- 1996-06
- Volume
- 1996
- Issue
- 06
- Pages
- 521-522
- ISSN
- 0936-5214 (ISSN-L)
- 1437-2096
- OpenAlex
- W2952967879
- Cited by
- 782
- References
- 0
- FWCI
- 5.98
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: An Improved One-pot Procedure for the Synthesis of Alkynes from Aldehydes. https://app.cochat.ai/papers/10.1055/s-1996-5474
- The paper
- Müller, S., Liepold, B., Roth, G. J., & Bestmann, H. J. (1996). An Improved One-pot Procedure for the Synthesis of Alkynes from Aldehydes. Synlett. https://doi.org/10.1055/s-1996-5474
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
