Effects of Oral Creatine-Pyruvate Supplementation in Cycling Performance
Abstract
A double-blind study was performed to evaluate the effects of oral creatine-pyruvate administration on exercise performance in well-trained cyclists. Endurance and intermittent sprint performance were evaluated before (pretest) and after (posttest) one week of creatine-pyruvate intake (Cr(pyr), 2 x 3.5 g x d-1, n = 7) or placebo (PL, n = 7). Subjects first performed a 1-hour time trial during which the workload could be adjusted at 5-min intervals. Immediately they did five 10-sec sprints interspersed by 2-min rest intervals. Tests were performed on an individual race bicycle that was mounted on an ergometer. Steady-state power production on average was about 235-245 W, which corresponded to blood lactate concentrations of 4-5 mmol x l -1 and heart rate in the range of 160-170 beats x min -1. Power outputs as well as blood lactate levels and heart rates were similar between Cr(pyr) and PL at all times. Total work performed during the 1-h trial was 872 +/- 44 KJ in PL versus 891 +/- 51 KJ in CR pyr. During the intermittent sprint test power peaked at about 800-1000 watt within 2-3 sec, decreasing by 15-20 % towards the end of each sprint. Peak and mean power outputs were similar between groups at all times. Peak lactate concentrations after the final sprint were approximately 11 mmol x l -1 in both groups during both the pretest and the posttest. It is concluded that one week of creatine-pyruvate supplementation at a rate of 7 g x d -1 does not beneficially impact on either en…
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7 days of 7 g per day CPY supplementation did not beneficially impact endurance capacity or intermittent sprint performance in well-trained cyclists.
“In this regard, 7 days of 7 g per day CPY supplementation did not beneficially impact endurance capacity or intermittent sprint performance in well-trained cyclists (Van Schuylenbergh et al. 2003), whereas 5 days of 7.5 g per day CPY intake increased paddling speed and resulted in decreased lactate concentrations in Olympic canoeists, suggesting an increase in aerobic metabolism (Nuuttilla 2000).”
From Analysis of the efficacy, safety, and regulatory status of novel forms of creatine (2011) · cites this paper as Van Schuylenbergh et al. 2003
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- Authors
- Van Schuylenbergh, R., Van Leemputte, M., & Hespel, P.
- Affiliations
- KU Leuven (BE)
- ORCID
- Hespel, P.
- Venue
- International Journal of Sports Medicine
- Publisher
- Georg Thieme Verlag KG
- Published
- 2003
- Volume
- 24
- Issue
- 2
- Pages
- 144-150
- ISSN
- 0172-4622 (ISSN-L)
- 1439-3964
- OpenAlex
- W1981666036
- Cited by
- 25
- References
- 0
- Citations by year
- 2026: 2 · 2022: 2 · 2021: 1 · 2020: 1 · 2016: 2 · 2015: 1 · 2014: 1 · 2013: 1 · 2012: 1
- FWCI
- 0.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Sports Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Physiology › Biochemical effects in animals
- Keywords
- dietary supplementation, cycling performance, endurance capacity, blood lactate, output power, trained cyclists
- MeSH terms
- Bicycling, Creatine, Double-Blind Method, Exercise Test, Humans, Male, Task Performance and Analysis, Pyruvic Acid, Lactic Acid, Dietary Supplements
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