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Cited by 344Doping in SportsPharmaceutical Quality and CounterfeitingPharmacological Effects and Assays

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Analysis of Non-Hormonal Nutritional Supplements for Anabolic-Androgenic Steroids - Results of an International Study

H. Geyer, Maria Kristina Parr, Ute Mareck, U. Reinhart, Yvonne Schrader, Wilhelm Schänzer·2004·International Journal of Sports Medicine
DOI 10.1055/s-2004-819955
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Abstract

Several recent studies have shown evidence of some nutritional supplements containing prohibited anabolic androgenic steroids, so-called prohormones, which were not declared on the label. Therefore, a broad-based investigation of the international nutritional supplement market was initiated to clarify the extent of this problem. From October 2000 until November 2001, 634 non-hormonal nutritional supplements were purchased in 13 countries from 215 different suppliers. Most supplements were bought in shops in the respective countries (578 samples = 91.2 %) and on the internet (52 samples = 8.2 %). 289 supplements were from prohormone-selling companies and 345 supplements came from companies which do not offer prohormones. After isolation from the supplement matrix 11 different anabolic androgenic steroids, mainly prohormones of testosterone and nandrolone, were analysed by gas-chromatography/mass spectrometry. Out of the 634 samples analysed 94 (14.8 %) contained anabolic androgenic steroids not declared on the label ("positive supplements"). We could not obtain reliable data for 66 samples (10.4 %) due to matrix effects. In relation to the total number of products purchased per country, most of the positive supplements were bought in the Netherlands (25.8 %), in Austria (22.7 %), in the UK (18.8 %) and the USA (18.8 %). According to the label, all positive supplements were from companies located in only five countries: the USA, the Netherlands, the UK, Italy and Germany. 21.1 % of the nutritional supplements from prohormone-selling companies contained anabolic androgenic steroids, whereas 9.6 % of the supplements from companies not selling prohormones were positive. The positive supplements showed anabolic androgenic steroid concentrations of 0.01 micro g/g up to 190 micro g/g. The administration of supplements containing nandrolone prohormones adding up to a total uptake of more than 1 micro g resulted in positive doping results for norandrosterone for several hours.

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Metadata

Authors
Geyer, H., Parr, M. K., Mareck, U., Reinhart, U., Schrader, Y., & Schänzer, W.
Affiliations
German Sport University Cologne (DE)
ORCID
Venue
International Journal of Sports Medicine
Publisher
Georg Thieme Verlag KG
Published
2004-02
Volume
25
Issue
2
Pages
124-129
ISSN
  • 0172-4622 (ISSN-L)
  • 1439-3964
DOI
10.1055/s-2004-819955
OpenAlex
W177183491
Cited by
344
References
0
Citations by year
2026: 8 · 2025: 9 · 2024: 7 · 2023: 14 · 2022: 19 · 2021: 10 · 2020: 21 · 2019: 13 · 2018: 32 · 2017: 22 · 2016: 16 · 2015: 19 · 2014: 18 · 2013: 21 · 2012: 13
FWCI
45.42
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Sports Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
International Olympic Committee
Topics
  • Social Sciences › Sociology and Political Science › Doping in Sports
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pharmaceutical Quality and Counterfeiting
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Pharmacological Effects and Assays
Keywords
anabolic steroids, prohormone, dietary supplements, doping in sport, supplement labeling
MeSH terms
Adult, Doping in Sports, Epitestosterone, Humans, Male, Middle Aged, Product Surveillance, Postmarketing, Testosterone, Dietary Supplements, Glucuronides, Internationality, Anabolic Agents

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