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Cited by 101Peripheral Artery Disease ManagementDiabetic Foot Ulcer Assessment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

High Prevalence of Peripheral Arterial Disease and Low Treatment Rates in Elderly Primary Care Patients with Diabetes

Lange, S., Diehm, C., Darius, H., Haberl, R., Allenberg, J., Pittrow, D., Schuster, A., von Stritzky, B. +2 more·2004·Experimental and Clinical Endocrinology & Diabetes
DOI 10.1055/s-2004-830408
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Abstract

Representative data on peripheral arterial disease (PAD) in community-based office practice are scarce while at the same time of high interest. Thus, we aimed to determine the prevalence of peripheral arterial disease (PAD), comorbidity of atherothrombotic manifestations, and treatment intensity among elderly diabetic patients in primary care. In this monitored cross-sectional study, 344 general practitioners throughout Germany determined the ankle-brachial index (ABI) of 6880 consecutive, unselected patients aged 65 years or older with bilateral Doppler ultrasound measurements. PAD was defined according to the recent American Heart Association guidelines (using the higher of the 2 systolic ankle pressures: ABI or = 6.5 % and/or intake of oral antidiabetic medication and/or application of insulin. 1.743 patients were classified as diabetics: the median disease duration was 6 years (1st; 3rd quartile: 2; 11), median HbA1c 6.6 % (5.9; 7.3), mean age 72.5 +/- 5.4 years, and 51.4 % were females. Diabetics had in comparison with non-diabetics a higher prevalence of PAD defined as ABI < 0.9 (26.3 % vs. 15.3 %, univariate odds ratio 2.0 [95 % confidence interval: 1.7; 2.3]), intermittent claudication (5.1 % vs. 2.1 %, OR: 2.5 [1.9; 3.4]), known CAD (16.1 % vs. 10.6 %, OR: 1.6 [1.4; 1.9]), and known CVD (6.8 % vs. 4.8 %; OR: 1.4 [1.2; 1.8]). 57.4 % of the diabetics with previously known PAD (as only atherothrombotic manifestation) received antiplatelet therapy (vs. 75.1 % with CAD an…

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  • In other screening studies, 26% of people with diabetes have been shown to have PAD.

    “Similarly, in other screening studies, 26% of people with diabetes have been shown to have PAD (234), and diabetes increased”

    From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2025 (2025) · cites this paper as [234]

  • In other screening studies, 26% of people with diabetes have been shown to have PAD, and diabetes increased the odds of having PAD by 85%.

    “Similarly, in other screening studies, 26% of people with diabetes have been shown to have PAD (224), and diabetes increased the odds of having PAD by 85% (225).”

    From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [224]

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Authors
Lange, S., Diehm, C., Darius, H., Haberl, R., Allenberg, J., Pittrow, D., Schuster, A., von Stritzky, B., Tepohl, G., & Trampisch, H.
Affiliations
  • Ruhr University Bochum (DE)
  • Heidelberg University (DE)
  • München Klinik (DE)
  • Technische Universität Dresden (DE)
ORCID
Venue
Experimental and Clinical Endocrinology & Diabetes
Publisher
Georg Thieme Verlag KG
Published
2004-12-02
Volume
112
Issue
10
Pages
566-573
ISSN
  • 0947-7349 (ISSN-L)
  • 1439-3646
DOI
10.1055/s-2004-830408
OpenAlex
W2083291499
Cited by
101
References
0
Citations by year
2026: 1 · 2025: 6 · 2024: 9 · 2023: 6 · 2022: 4 · 2021: 8 · 2020: 5 · 2019: 6 · 2018: 3 · 2017: 2 · 2016: 8 · 2015: 4 · 2014: 3 · 2013: 2 · 2012: 3
FWCI
3.47
Type
journal article
Language
en
Open access
closed
Locations
  • Experimental and Clinical Endocrinology & Diabetes (publishedVersion)
  • PubMed (publishedVersion)
Funders
Sanofi
Topics
  • Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetic Foot Ulcer Assessment and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
peripheral arterial disease, diabetes mellitus, elderly patients, ankle-brachial index, intermittent claudication, coronary artery disease, cerebrovascular disease, antiplatelet therapy, primary care, prevalence, screening, treatment rates, comorbidities, Doppler ultrasound, HbA1c, amputation, cardiovascular risk
MeSH terms
Aged, Aged, 80 and over, Arterial Occlusive Diseases, Cross-Sectional Studies, Diabetic Angiopathies, Female, Germany, Humans, Male, Platelet Aggregation Inhibitors, Quality Assurance, Health Care, Reference Values, Risk Factors, Systole, Prevalence, Odds Ratio, Peripheral Vascular Diseases

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