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Recent Advances in Pd/C-Catalyzed Coupling Reactions
Abstract
A practical approach to multifunctional compounds through palladium on activated carbon (Pd/C)-catalyzed coupling reactions is described. A close correlation of the properties of the Pd/C with reaction efficiency has been observed and depends largely upon the type of reaction. A critical role of the activated carbon is to help palladium disperse sufficiently on the solid support to form the active palladium complex without aggregating to inactive palladium black. The use of Pd/C avoids contamination of the product with palladium and expedites recovery of the metal. The reactions are practical and have been applied to cost-effective large-scale production of multifunctional compounds for drug synthesis.
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Citations
Cited by
Carbon−Carbon Coupling Reactions Catalyzed by Heterogeneous Palladium Catalysts
Yin, & Liebscher, J. (2007) · Chemical Reviews · doi:10.1021/cr0505674 · Cited by 2,085
Libra, J. A., Ro, K. S., Kammann, C., Funke, A., Berge, N. D., Neubauer, Y., Titirici, M.-M., Fühner, C., Bens, O., Kern, J., et al. (2011) · Biofuels · doi:10.4155/bfs.10.81 · Cited by 1,756
Efficient, Selective, and Recyclable Palladium Catalysts in Carbon−Carbon Coupling Reactions
Molnár, Á. (2011) · Chemical Reviews · doi:10.1021/cr100355b · Cited by 1,042
Recent advances in metallogels
Tam, A. Y.-Y., & Yam, V. W.-W. (2013) · Chemical Society Reviews · doi:10.1039/c2cs35354g · Cited by 630
Alonso, F., Beletskaya, I. P., & Yus, M. (2008) · Tetrahedron · doi:10.1016/j.tet.2007.12.036 · Cited by 532
Metadata
- Authors
- Seki, M.
- Venue
- Synthesis
- Publisher
- Georg Thieme Verlag KG
- Published
- 2006-08-15
- Volume
- 2006
- Issue
- 18
- Pages
- 2975-2992
- ISSN
- 0039-7881 (ISSN-L)
- 1437-210X
- OpenAlex
- W2950265806
- Cited by
- 191
- References
- 0
- FWCI
- 7.38
- Type
- journal article
- Language
- en
- Open access
- closed
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