Cited by 117Muscle metabolism and nutritionSports Performance and TrainingBiochemical effects in animals

Creatine Supplementation as an Ergogenic Aid for Sports Performance in Highly Trained Athletes: A Critical Review

Mujika, I., Padilla, S.·1997·International Journal of Sports Medicine

Abstract

Creatine supplementation has become a common practice among competition athletes participating in different sports over the last few years. The mechanism by which supplementary creatine could have potential ergogenic effects would be an increased muscle creatine and phosphocreatine concentration, leading to a higher rate of ATP resynthesis, a delay in the onset of muscular fatigue and a facilitated recovery during repeated bouts of high-intensity exercise. A critical review of the literature reveals that these ergogenic effects, when found, have been generally shown in untrained subjects performing several exercise bouts under laboratory conditions. The limited body of scientific data available concerning highly trained athletes performing single competition-like exercise tasks indicates that this type of population does not benefit from creatine supplementation. Therefore, the widespread use of creatine ingestion to improve competition performance does not seem to be justified. The potential interest of creatine supplementation for elite athletes could be related to an increased ability to perform repeated high-intensity exercise bouts, either during training or during competition in sports in which repeated efforts are required (e.g. soccer, basketball), but this possibility needs scientific confirmation.

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Crossref · 10.1055/s-2007-972670

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  • Exogenous creatine has been shown to increase muscle volume and has been associated with a marginal improvement in performance for some adult athletes.

    “Although exogenous creatine has been shown to increase muscle volume and has been associated with a marginal improvement in performance for some adult athletes”
  • The results of this review show that there is no evidence to support supplementation as an effective strategy to consistently improve athletic performance in an adolescent population.

    “the results of this review show that there is no evidence to support supplementation as effective strategy to consistently improve athletic performance in an adolescent population.48,49”

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Cited by 117

Authors
Mujika, I., & Padilla, S.
Venue
International Journal of Sports Medicine
Published
1997-10
Volume
18
Issue
07
Pages
491-496
ISSN
  • 0172-4622 (ISSN-L)
  • 1439-3964
OpenAlex
W2075766453
Cited by
117
References
0
Citations by year
2026: 2 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 6 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 5 · 2014: 2 · 2013: 4 · 2012: 2
FWCI
2.48
Type
journal article
Language
en
Open access
closed
Locations
  • International Journal of Sports Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Physiology › Biochemical effects in animals
Keywords
creatine supplementation, ergogenic aids, athletic performance, highly trained athletes, phosphocreatine, ATP resynthesis, muscle fatigue, elite athletes, high-intensity exercise
MeSH terms
Adenosine Triphosphate, Basketball, Creatine, Energy Metabolism, Physical Exertion, Fatigue, Humans, Motor Activity, Phosphocreatine, Physical Endurance, Physical Fitness, Soccer, Sports, Exercise, Muscle, Skeletal, Muscle Fatigue, Dietary Supplements

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