Creatine Supplementation as an Ergogenic Aid for Sports Performance in Highly Trained Athletes: A Critical Review
Abstract
Creatine supplementation has become a common practice among competition athletes participating in different sports over the last few years. The mechanism by which supplementary creatine could have potential ergogenic effects would be an increased muscle creatine and phosphocreatine concentration, leading to a higher rate of ATP resynthesis, a delay in the onset of muscular fatigue and a facilitated recovery during repeated bouts of high-intensity exercise. A critical review of the literature reveals that these ergogenic effects, when found, have been generally shown in untrained subjects performing several exercise bouts under laboratory conditions. The limited body of scientific data available concerning highly trained athletes performing single competition-like exercise tasks indicates that this type of population does not benefit from creatine supplementation. Therefore, the widespread use of creatine ingestion to improve competition performance does not seem to be justified. The potential interest of creatine supplementation for elite athletes could be related to an increased ability to perform repeated high-intensity exercise bouts, either during training or during competition in sports in which repeated efforts are required (e.g. soccer, basketball), but this possibility needs scientific confirmation.
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Exogenous creatine has been shown to increase muscle volume and has been associated with a marginal improvement in performance for some adult athletes.
“Although exogenous creatine has been shown to increase muscle volume and has been associated with a marginal improvement in performance for some adult athletes”
From Creatine supplementation in the pediatric and adolescent athlete-- A literature review (2023) · cites this paper as [49]
The results of this review show that there is no evidence to support supplementation as an effective strategy to consistently improve athletic performance in an adolescent population.
“the results of this review show that there is no evidence to support supplementation as effective strategy to consistently improve athletic performance in an adolescent population.48,49”
From Creatine supplementation in the pediatric and adolescent athlete-- A literature review (2023) · cites this paper as [49]
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Cited by 117
- Authors
- Mujika, I., & Padilla, S.
- Venue
- International Journal of Sports Medicine
- Publisher
- Georg Thieme Verlag KG
- Published
- 1997-10
- Volume
- 18
- Issue
- 07
- Pages
- 491-496
- ISSN
- 0172-4622 (ISSN-L)
- 1439-3964
- OpenAlex
- W2075766453
- Cited by
- 117
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 3 · 2022: 2 · 2021: 6 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2015: 5 · 2014: 2 · 2013: 4 · 2012: 2
- FWCI
- 2.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Sports Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Physiology › Biochemical effects in animals
- Keywords
- creatine supplementation, ergogenic aids, athletic performance, highly trained athletes, phosphocreatine, ATP resynthesis, muscle fatigue, elite athletes, high-intensity exercise
- MeSH terms
- Adenosine Triphosphate, Basketball, Creatine, Energy Metabolism, Physical Exertion, Fatigue, Humans, Motor Activity, Phosphocreatine, Physical Endurance, Physical Fitness, Soccer, Sports, Exercise, Muscle, Skeletal, Muscle Fatigue, Dietary Supplements
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