Accelerating the Clinical Workflow Using the Sepsis Prediction and Optimization of Therapy (SPOT) Tool for Real-Time Clinical Monitoring

Abstract

SummaryThe early identification and diagnosis of sepsis remains a challenge in most health care settings. To promote identification and treatment of sepsis earlier in the progression of the disease, HCA Healthcare implemented a series of performance improvement initiatives and augmented this with an automated, real-time algorithm to detect sepsis. We leveraged the scale of our data to create the algorithm and then implemented it into the workflows of 173 distinct acute care hospitals, demonstrating reproducibility and contributing to a decline in sepsis-related mortality over a 6-year period. This algorithm, referred to as SPOT — Sepsis Prediction and Optimization of Therapy — can be incorporated into ongoing sepsis detection, prevention, and treatment initiatives.