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Augmentation of the Plasma Nor-Epinephrine Response to Exercise in Patients with Congestive Heart Failure
Abstract
THE manner in which the cardiovascular system responds to the increased metabolic demands of muscular exercise is of considerable interest to the clinician and physiologist. It has been suggested that the sympathetic nervous system plays an important part in mediating this response in normal man.1 2 3 4 5 In patients in whom the cardiac reserve is diminished, the normal increase of cardiac output during exercise is attenuated, or even abolished.6 , 7 It is not known to what extent the sympathetic nervous system is called into play under these circumstances. Diminished activity of this important reserve mechanism could be a factor in the abnormal cardiac . . .
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Citations
Cited by
Plasma Norepinephrine as a Guide to Prognosis in Patients with Chronic Congestive Heart Failure
Cohn, J. N., Levine, T. B., Olivari, M. T., Garberg, V., Lura, D., Francis, G. S., Simon, A. B., & Rector, T. (1984) · New England Journal of Medicine · doi:10.1056/nejm198409273111303 · Cited by 3,125
Braunwald, E. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0800239 · Cited by 1,257
Self-citationAnker, S. D., Chua, T. P., Ponikowski, P., Harrington, D., Swan, J. W., Kox, W. J., Poole-Wilson, P. A., & Coats, A. J. S. (1997) · Circulation · doi:10.1161/01.cir.96.2.526 · Cited by 800
The Neurohumoral Axis in Congestive Heart Failure
FRANCIS, G. S., GOLDSMITH, S. R., LEVINE, T. B., OLIVARI, M. T., & COHN, J. N. (1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-101-3-370 · Cited by 600
The human sympathetic nervous system: its relevance in hypertension and heart failure
Parati, G., & Esler, M. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs041 · Cited by 538
Metadata
- Authors
- Chidsey, C. A., Harrison, D. C., & Braunwald, E.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1962-09-27
- Volume
- 267
- Issue
- 13
- Pages
- 650-654
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2340670561
- Cited by
- 436
- References
- 0
- FWCI
- 12.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chidsey, C. A., Harrison, D. C., & Braunwald, E. (1962). Augmentation of the Plasma Nor-Epinephrine Response to Exercise in Patients with Congestive Heart Failure. New England Journal of Medicine. https://doi.org/10.1056/nejm196209272671305
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.