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Massive Calcification of the Mitral Annulus: A Clinicopathological Study of Fourteen Cases

Korn, David, DeSanctis, Roman W., Sell, Stewart·1962·New England Journal of Medicine

Abstract

CALCIFICATION of the annulus fibrosus of the mitral valve is commonly found in older people at autopsy.1 2 3 4 5 6 7 8 Although this process can be a sequela of rheumatic,7 , 8 rheumatoid9 and other types of endocarditis, pathological evidence of previous inflammation is often absent.10 , 11 The lesion is generally regarded as the end stage of a degenerative process.1 2 3 4 5 6 7 8 Recently, severe calcification of the mitral annulus, with resultant anatomic deformity of the orifice, has been found in 5 patients at the Massachusetts General Hospital at post-mortem examination. In none was there pathological evidence of healed rheumatic heart disease. These unusual findings stimulated a search of the . . .

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Metadata

Authors
Korn, D., DeSanctis, R. W., & Sell, S.
Venue
New England Journal of Medicine
Published
1962-11
Volume
267
Issue
18
Pages
900-909
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2320595911
Cited by
260
References
0
FWCI
6.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Massive Calcification of the Mitral Annulus: A Clinicopathological Study of Fourteen Cases. https://app.cochat.ai/papers/10.1056/nejm196211012671802
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Korn, D., DeSanctis, R. W., & Sell, S. (1962). Massive Calcification of the Mitral Annulus: A Clinicopathological Study of Fourteen Cases. New England Journal of Medicine. https://doi.org/10.1056/nejm196211012671802

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.