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Effects of Mitral-Valve Replacement on the Pulmonary Vascular Dynamics of Patients with Pulmonary Hypertension
Abstract
THE development of an elevation of the pulmonary vascular resistance is a common complication of severe mitral-valve disease, and this abnormality has been attributed to a combination of obliterative changes in the pulmonary vascular bed and pulmonary vasoconstriction.1 2 3 In many patients the elevation of pulmonary vascular resistance is extreme and constitutes the major hemodynamic burden faced by the right ventricle.4 Under these circumstances the secondary changes in the pulmonary vascular bed become primarily responsible for many of the clinical findings, including ventricular failure. In view of these considerations determination of the extent to which these abnormalities in the pulmonary circulation . . .
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Citations
Cited by
Updated clinical classification of pulmonary hypertension
Simonneau, G., Gatzoulis, M. A., Adatia, I., Celermajer, D., Denton, C., Ghofrani, A., Gomez Sanchez, M. A., Krishna Kumar, R., Landzberg, M., Machado, R. F., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.10.029 · Cited by 4,191
Updated Clinical Classification of Pulmonary Hypertension
Simonneau, G., Robbins, I. M., Beghetti, M., Channick, R. N., Delcroix, M., Denton, C. P., Elliott, C. G., Gaine, S. P., Gladwin, M. T., Jing, Z.-C., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.04.012 · Cited by 2,093
The problem of valve prosthesis-patient mismatch.
Rahimtoola, S. H. (1978) · Circulation · doi:10.1161/01.cir.58.1.20 · Cited by 853
Thenappan, T., Shah, S. J., Gomberg-Maitland, M., Collander, B., Vallakati, A., Shroff, P., & Rich, S. (2011) · Circulation Heart Failure · doi:10.1161/circheartfailure.110.958801 · Cited by 289
Association of the metabolic syndrome with pulmonary venous hypertension
Robbins, I. M., Newman, J. H., Johnson, R. F., Hemnes, A. R., Fremont, R. D., Piana, R. N., Zhao, D. X., & Byrne, D. W. (2009) · Chest · doi:10.1378/chest.08-2008 · Cited by 171
Metadata
- Authors
- Braunwald, E., Braunwald, N. S., Ross, J., & Morrow, A. G.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1965-09-02
- Volume
- 273
- Issue
- 10
- Pages
- 509-514
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2341668027
- Cited by
- 203
- References
- 0
- FWCI
- 20.70
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Effects of Mitral-Valve Replacement on the Pulmonary Vascular Dynamics of Patients with Pulmonary Hypertension. https://app.cochat.ai/papers/10.1056/nejm196509022731001
- The paper
- Braunwald, E., Braunwald, N. S., Ross, J., & Morrow, A. G. (1965). Effects of Mitral-Valve Replacement on the Pulmonary Vascular Dynamics of Patients with Pulmonary Hypertension. New England Journal of Medicine. https://doi.org/10.1056/nejm196509022731001
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
