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Bronchial Response to Beta-Adrenergic Blockade
Abstract
ASTHMA can be defined as a disease of the bronchi producing diffuse, reversible bronchial obstruction. The bronchial tree of patients with asthma is hypersensitive to the effects of dust, cold air, histamine, methacholine and pollen extracts, so that bronchial obstruction roughly proportional to the severity of the asthma can be demonstrated after such exposures.2 3 4 5 The cause of this bronchial hypersensitivity is not known. Patients with other forms of chronic obstructive pulmonary disease or allergic rhinitis have similar but less marked bronchial sensitivity to these materials.5 , 6 A series of investigations in animals has led to the hypothesis that a partial beta-adrenergic . . .
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Citations
Cited by
Reactive Airways Dysfunction Syndrome (RADS)
Brooks, S. M., Weiss, M. A., & Bernstein, I. L. (1985) · Chest · doi:10.1378/chest.88.3.376 · Cited by 678
Cardioselective beta-blockers for chronic obstructive pulmonary disease
Salpeter, S. R., Ormiston, T. M., & Salpeter, E. E. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003566.pub2 · Cited by 381
Anderson, S. D., Silverman, M., König, P., & Godfrey, S. (1975) · British Journal of Diseases of the Chest · doi:10.1016/0007-0971(75)90053-4 · Cited by 277
Cardioselective β-Blockers in Patients with Reactive Airway Disease: A Meta-Analysis
Salpeter, S. R., Ormiston, T. M., & Salpeter, E. E. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-9-200211050-00035 · Cited by 266
Metadata
- Authors
- Zaid, G., & Beall, G. N.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1966-09-15
- Volume
- 275
- Issue
- 11
- Pages
- 580-584
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2340753777
- Cited by
- 202
- References
- 0
- FWCI
- 25.10
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.