The DOI matches its Crossref record.
Similarities between Neurologic Effects of L-Dopa and of Apomorphine
Abstract
L-DOPA is a precursor for the biosynthesis of both melanins and catecholamines. Both groups of substances are diminished within the Parkinsonian brain.1 2 3 L-dopa administration might therefore increase both melanins and catecholamines.4 The side effects of L-dopa were assigned to dopamine instead of melanin5 because they paralleled the effects of apomorphine, which has chemical similarities to dopamine6 and activates dopaminergic receptors in laboratory animals.6 7 8 The therapeutic effects of L-dopa might also be assigned to dopamine if they could be duplicated by apomorphine.4 , 9 , 10 We have found that subcutaneous administration of apomorphine to patients with selected neurologic disorders has temporarily changed the neurologic . . .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Calne, D. B., Teychenne, P. F., Claveria, L. E., Eastman, R., Greenacre, J. K., & Petrie, A. (1974) · BMJ · doi:10.1136/bmj.4.5942.442 · Cited by 311
Influences of cholinergic mechanisms on the function and turnover of brain dopamine
Andén, N.-E., & Bédard, P. (1971) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.1971.tb08686.x · Cited by 269
Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
Hare, D. J., Adlard, P. A., Doble, P. A., & Finkelstein, D. I. (2013) · Metallomics · doi:10.1039/c2mt20164j · Cited by 78
Metadata
- Authors
- Cotzias, G. C., Papavasiliou, P. S., Fehling, C., Kaufman, B., & Mena, I.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1970-01
- Volume
- 282
- Issue
- 1
- Pages
- 31-33
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2312905901
- Cited by
- 271
- References
- 0
- FWCI
- 33.55
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Similarities between Neurologic Effects of L-Dopa and of Apomorphine. https://app.cochat.ai/papers/10.1056/nejm197001012820107
- The paper
- Cotzias, G. C., Papavasiliou, P. S., Fehling, C., Kaufman, B., & Mena, I. (1970). Similarities between Neurologic Effects of L-Dopa and of Apomorphine. New England Journal of Medicine. https://doi.org/10.1056/nejm197001012820107
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
