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Cited by 287

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Prevalence, Incidence and Persistence of EB Virus Antibody in Young Adults

Niederman, J. C., Evans, A. S., Subrahmanyan, L., McCollum, R. W.·1970·New England Journal of Medicine

Abstract

The prevalence rate for antibody to EB virus measured by the indirect immunofluorescence technic in 1084 young adults varied from 26 to 87 per cent depending on age and geographic area. In a prospective study of 150 Yale students 53 had EBV antibody on entry into college; 43 of 97 students lacking antibody had seroconversion during the next four to eight years, 28 with recognized clinical infectious mononucleosis and 15 with inapparent or unrecognized illness. This was an infection rate of 11.1 per cent per year in the susceptible group. Of 164 Peace Corps volunteers 76 per cent had detectable anti-EBV titers on entrance into service, and of 30 lacking antibody 27 per cent were infected over one year while working in Colombia, South America. In Yale students EBV antibody was always present in serum specimens obtained as long as eight years after clinical or subclinical infection, usually at levels of 1:40 or higher.

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Metadata

Authors
Niederman, J. C., Evans, A. S., Subrahmanyan, L., & McCollum, R. W.
Venue
New England Journal of Medicine
Published
1970-02-12
Volume
282
Issue
7
Pages
361-365
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2313147231
Cited by
287
References
0
FWCI
26.88
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Prevalence, Incidence and Persistence of EB Virus Antibody in Young Adults. https://app.cochat.ai/papers/10.1056/nejm197002122820704
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Niederman, J. C., Evans, A. S., Subrahmanyan, L., & McCollum, R. W. (1970). Prevalence, Incidence and Persistence of EB Virus Antibody in Young Adults. New England Journal of Medicine. https://doi.org/10.1056/nejm197002122820704

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.