The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Effect of Carotid Endarterectomy on Carotid Chemoreceptor and Baroreceptor Function in Man
Abstract
The ventilatory response to inhaled carbon dioxide was measured during hyperoxia (Pao2 over 200 torr) and hypoxia (Pao2 of 40 torr) in 14 patients before and one to nine weeks after carotid endarterectomy for transient attacks of cerebral ischemia. Ventilatory response was unchanged in the seven patients undergoing unilateral carotid endarterectomy. All seven patients undergoing staged bilateral procedures lost their ventilatory response to hypoxia and showed a 5.8-torr increase in mean resting Paco2. In four patients studied, hypoxia at constant Paco2 increased systolic blood pressure before and clearly decreased it after bilateral surgery. Bilateral carotid endarterectomy results in a loss of carotid-body function, with loss of the usual compensatory respiratory or circulatory responses to hypoxia. Baroreceptor activity, as measured by the standard Valsalva maneuver, was minimal before and showed no consistent change as a result of surgery.
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Cites
Diminished Baroreflex Sensitivity in High Blood Pressure
BRISTOW, J. D., HONOUR, A. J., PICKERING, G. W., SLEIGHT, P., & SMYTH, H. S. (1969) · Circulation · doi:10.1161/01.cir.39.1.48 · Cited by 569
Respiratory insensitivity to hypoxia in chronically hypoxic man
Severinghaus, J. W., Bainton, C. R., & Carcelen, A. (1966) · Respiration Physiology · doi:10.1016/0034-5687(66)90049-1 · Cited by 278
Self-citationBevegård, B. S., & Shepherd, J. T. (1966) · Journal of Clinical Investigation · doi:10.1172/jci105317 · Cited by 236
Effects of Valsalva's Man uvre on the Normal and Failing Circulation
Sharpey-Schafer, E. P. (1955) · BMJ · doi:10.1136/bmj.1.4915.693 · Cited by 228
Holton, P., & Wood, J. B. (1965) · The Journal of Physiology · doi:10.1113/jphysiol.1965.sp007767 · Cited by 111
Respiratory sensitivity to acute hypoxia in man born at sea level living at high altitude.
Sorensen, S. C., & Severinghaus, J. W. (1968) · Journal of Applied Physiology · doi:10.1152/jappl.1968.25.3.211 · Cited by 63
Self-citationCirculatory Reflexes in Patients with Cerebrovascular Disease
Appenzeller, O., & Descarries, L. (1964) · New England Journal of Medicine · doi:10.1056/nejm196410152711604 · Cited by 61
Cited by
Selective Potentiation of Peripheral Chemoreflex Sensitivity in Obstructive Sleep Apnea
Narkiewicz, K., van de Borne, P. J. H., Pesek, C. A., Dyken, M. E., Montano, N., & Somers, V. K. (1999) · Circulation · doi:10.1161/01.cir.99.9.1183 · Cited by 560
Kronenberg, R. S., & Drage, C. W. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107363 · Cited by 394
The sympathetic nervous system and obstructive sleep apnea: implications for hypertension
Narkiewicz, K., & Somers, V. K. (1997) · Journal of Hypertension · doi:10.1097/00004872-199715120-00062 · Cited by 254
Metadata
- Authors
- Wade, J. G., Larson, C. P., Hickey, R. F., Ehrenfeld, W. K., & Severinghaus, J. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1970-04-09
- Volume
- 282
- Issue
- 15
- Pages
- 823-829
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2010296843
- Cited by
- 270
- References
- 7
- FWCI
- 16.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wade, J. G., Larson, C. P., Hickey, R. F., Ehrenfeld, W. K., & Severinghaus, J. W. (1970). Effect of Carotid Endarterectomy on Carotid Chemoreceptor and Baroreceptor Function in Man. New England Journal of Medicine. https://doi.org/10.1056/nejm197004092821501
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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