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Gallstone Migration as a Cause of Acute Pancreatitis
Abstract
Stools were screened for gallstones in 36 patients with acute pancreatitis associated with gallstones. These patients had typical clinical evidence of pancreatitis with transiently elevated serum amylase and bilirubin concentrations. Another 36 patients with gallstones but without acute pancreatitis served as controls. Gallstones were found in the feces of 34 out of 36 patients with pancreatitis, but in only three out of the 36 control cases. In the former group, the finding was usually preceded by a relief of the symptoms and a rapid decrease of serum amylase and bilirubin concentrations. The calculi found in the stools and those found in the biliary tracts of the patients at operation were identical as determined by gross inspection and chemical analysis. These findings suggest that acute pancreatitis associated with gallstone disease is frequently caused by transient blockage of the ampulla of Vater by migrating gallstones. (N Engl J Med 290:484–487, 1974)
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Citations
Cited by
American College of Gastroenterology guideline: management of acute pancreatitis
Tenner, S., Baillie, J., DeWitt, J., & Vege, S. S. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.218 · Cited by 2,327
IAP Guidelines for the Surgical Management of Acute Pancreatitis
Uhl, W. H., Warshaw, A. L., IMRIE, C. W., Bassi, C., McKay, C. J., Lankisch, P. G., Carter, R., Magno, E. D., Banks, P. A., Whitcomb, D. C., et al. (2002) · Pancreatology · doi:10.1159/000071269 · Cited by 773
EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones
(2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.03.005 · Cited by 576
Management of the critically ill patient with severe acute pancreatitis
Nathens, A. B., Curtis, J. R., Beale, R. J., Cook, D. J., Moreno, R. P., Romand, J.-A., Skerrett, S. J., Stapleton, R. D., Ware, L. B., & Waldmann, C. S. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000148222.09869.92 · Cited by 357
The Role of Oxygen-derived Free Radicals in the Pathogenesis of Acute Pancreatitis
SANFEY, H., BULKLEY, G. B., & CAMERON, J. L. (1984) · Annals of Surgery · doi:10.1097/00000658-198410000-00003 · Cited by 295
Metadata
- Authors
- Acosta, J. M., & Ledesma, C. L.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1974-02-28
- Volume
- 290
- Issue
- 9
- Pages
- 484-487
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2340505485
- Cited by
- 628
- References
- 0
- FWCI
- 13.87
- Type
- journal article
- Language
- en
- Open access
- closed
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- Acosta, J. M., & Ledesma, C. L. (1974). Gallstone Migration as a Cause of Acute Pancreatitis. New England Journal of Medicine. https://doi.org/10.1056/nejm197402282900904
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
