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Cited by 2,447

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Polymyositis and Dermatomyositis: (Second of Two Parts)

Bohan, Anthony, Peter, James B.·1975·New England Journal of Medicine

Abstract

Laboratory FeaturesElevation of sarcoplasmic enzymes in serum (creatine phosphokinase, aldolase, transaminases and lactic dehydrogenase) is valuable both for diagnosis and for following the clinical activity and response to treatment. Although some state that the transaminases are the most reliable,31,33,35 most authorities favor the creatine phosphokinase.2These serum enzymes are not infallible guidelines, for occasionally they remain entirely within the normal range despite active myositis1,51; likewise, when muscle atrophy is extensive in long standing disease, the enzymes may be normal despite active myositis. Motor-neuron diseases, Duchenne muscular dystrophy and other dystrophies, metabolic disorders, endocrinopathies, toxins . . .

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Metadata

Authors
Bohan, A., & Peter, J. B.
Venue
New England Journal of Medicine
Published
1975-02-20
Volume
292
Issue
8
Pages
403-407
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W184510336
Cited by
2,447
References
0
FWCI
4.78
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Polymyositis and Dermatomyositis: (Second of Two Parts). https://app.cochat.ai/papers/10.1056/nejm197502202920807
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Bohan, A., & Peter, J. B. (1975). Polymyositis and Dermatomyositis: (Second of Two Parts). New England Journal of Medicine. https://doi.org/10.1056/nejm197502202920807

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.