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Spinal Epidural Abscess
Abstract
Thirty-nine patients with spinal epidural abscess were evaluated at the Massachusetts General Hospital between 1947 and 1974. Twenty had acute symptoms, and purulent epidural collections were present; 19 had prolonged courses, and epidural granulation tissue was observed at operation. Staphylococcus aureus was the most common etiologic agent (57 per cent), followed by streptococci (18 per cent) and gram-negative bacilli (13 per cent). The source of infection was osteomyelitis in 38 per cent of cases and bacteremia in 26 per cent. In 16 per cent epidural abscess was due to postoperative infection. The progression from spinal ache to root pain to weakness followed by paralysis continues to be characteristic of spinal epidural abscess. Although the disease is uncommon, the complications are so serious that prompt diagnosis and treatment are of paramount importance. The combination of back pain with fewer and local tenderness is an indication for cerebrospinal-fluid examination and, depending on the results, immediate performance of myelography.
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Citations
Cited by
Darouiche, R. O. (2006) · New England Journal of Medicine · doi:10.1056/nejmra055111 · Cited by 685
Spinal epidural abscess: clinical presentation, management, and outcome
Curry, W. T., Hoh, B. L., Amin-Hanjani, S., & Eskandar, E. N. (2005) · Surgical Neurology · doi:10.1016/j.surneu.2004.08.081 · Cited by 309
Jenkins, K., & Baker, A. B. (2003) · Anaesthesia · doi:10.1046/j.1365-2044.2003.03410.x · Cited by 150
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Metadata
- Authors
- Baker, A. S., Ojemann, R. G., Swartz, M. N., & Richardson, E. P.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1975-09-04
- Volume
- 293
- Issue
- 10
- Pages
- 463-468
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W3149836132
- Cited by
- 781
- References
- 0
- FWCI
- 7.60
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Spinal Epidural Abscess. https://app.cochat.ai/papers/10.1056/nejm197509042931001
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- Baker, A. S., Ojemann, R. G., Swartz, M. N., & Richardson, E. P. (1975). Spinal Epidural Abscess. New England Journal of Medicine. https://doi.org/10.1056/nejm197509042931001
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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
