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Platelet Physiology and Abnormalities of Platelet Function: (First of Two Parts)
Abstract
THE blood platelets, approximately 2 μm in diameter and numbering 200,000 to 400,000 per cubic millimeter, are produced in the megakaryocytes of the bone marrow by the coalescence of cytoplasmic membranes formed by invaginations of the megakaryocyte surface.1 Under normal circumstances, platelets circulate in the blood for 10 days as smooth, disk-shaped cells that are nonadherent to each other and to normal vascular endothelium. Their unique biologic properties are the changes that occur when the endothelium is broken or when disruption of the vessel allows the blood to come into contact with elements of the vessel . . .
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Cited by
The Biosynthesis of Collagen and Its Disorders
Prockop, D. J., Kivirikko, K. I., Tuderman, L., & Guzman, N. A. (1979) · New England Journal of Medicine · doi:10.1056/nejm197907123010204 · Cited by 574
Savage, B., Shattil, S. J., & Ruggeri, Z. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)49910-9 · Cited by 314
Truncated Newton methods and the modeling of complex immersed elastic structures
Fauci, L. J., & Fogelson, A. L. (1993) · Communications on Pure and Applied Mathematics · doi:10.1002/cpa.3160460602 · Cited by 94
Metadata
- Authors
- Weiss, H. J.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1975-09-11
- Volume
- 293
- Issue
- 11
- Pages
- 531-541
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1992650719
- Cited by
- 445
- References
- 0
- FWCI
- 32.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Weiss, H. J. (1975). Platelet Physiology and Abnormalities of Platelet Function: (First of Two Parts). New England Journal of Medicine. https://doi.org/10.1056/nejm197509112931105
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
