The DOI matches its Crossref record.
Chromosomal Deletion and Retinoblastoma
Abstract
Retinoblastoma occurs at a very high rate among two groups of genetically predisposed persons: those who inherit the tumor potential with a dominant mode of transmission, and those who bear a deletion of the long arm of chromosome 13 in all their somatic cells. The latter group is particularly important because it is the only instance in animal or man in which a specific chromosomal abnormality can occur prezygotically and consistently predispose to a specific tumor. We report below a new case of this deletion and consider its relation to previously reported cases and the relation between the two genetic . . .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
Cavenee, W. K., Dryja, T. P., Phillips, R. A., Benedict, W. F., Godbout, R., Gallie, B. L., Murphree, A. L., Strong, L. C., & White, R. L. (1983) · Nature · doi:10.1038/305779a0 · Cited by 1,920
The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
Buchkovich, K., Duffy, L. A., & Harlow, E. (1989) · Cell · doi:10.1016/0092-8674(89)90508-4 · Cited by 995
Vogel, F. (1979) · Human Genetics · doi:10.1007/bf00284597 · Cited by 438
Risk of Second Malignancies in Survivors of Retinoblastoma: More Than 40 Years of Follow-up
Marees, T., Moll, A. C., Imhof, S. M., de Boer, M. R., Ringens, P. J., & van Leeuwen, F. E. (2008) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/djn394 · Cited by 286
One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma
Corson, T. W., & Gallie, B. L. (2007) · Genes, Chromosomes and Cancer · doi:10.1002/gcc.20457 · Cited by 278
Metadata
- Authors
- Knudson, A. G., Meadows, A. T., Nichols, W. W., & Hill, R.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1976-11-11
- Volume
- 295
- Issue
- 20
- Pages
- 1120-1123
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2018540952
- Cited by
- 281
- References
- 0
- FWCI
- 39.68
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Chromosomal Deletion and Retinoblastoma. https://app.cochat.ai/papers/10.1056/nejm197611112952007
- The paper
- Knudson, A. G., Meadows, A. T., Nichols, W. W., & Hill, R. (1976). Chromosomal Deletion and Retinoblastoma. New England Journal of Medicine. https://doi.org/10.1056/nejm197611112952007
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
