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Cited by 773

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Real-Time Radionuclide Cineangiography in the Noninvasive Evaluation of Global and Regional Left Ventricular Function at Rest and during Exercise in Patients with Coronary-Artery Disease

Borer, Jeffrey S., Bacharach, Stephen L., Green, Michael V., Kent, Kenneth M., Epstein, Stephen E., Johnston, Gerald S., Mack, Bonnie·1977·New England Journal of Medicine

Abstract

Although coronary angiography defines regions of potential ischemia in patients with coronary-artery disease, accurate assessment of the presence and functional importance of ischemia requires appraisal of regional and global left ventricular function during stress. To perform such assessment, we developed a noninvasive real-time radionuclide cineangiographic procedure permitting continuous monitoring and analysis of left ventricular function during exercise. In 11 patients with coronary disease who had normal regional and global ventricular function at rest, new regions of dysfunction developed during exercise (P less than 0.001), and in 10, global ejection fraction dropped 7 to 47 per cent. Fourteen age-matched normal subjects were studied; during exercise none had regional dysfunction, and each increased global ejection fraction (average increase, 23 +/- 3 per cent [+/-S.E.], P less than 0.001 as compared with patients with coronary disease). Radionuclide cineangiography during exercise permits accurate assessment of the presence and functional severity of ischemic heart disease.

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Metadata

Authors
Borer, J. S., Bacharach, S. L., Green, M. V., Kent, K. M., Epstein, S. E., Johnston, G. S., & Mack, B.
Venue
New England Journal of Medicine
Published
1977-04-14
Volume
296
Issue
15
Pages
839-844
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2335706440
Cited by
773
References
6
FWCI
90.95
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Real-Time Radionuclide Cineangiography in the Noninvasive Evaluation of Global and Regional Left Ventricular Function at Rest and during Exercise in Patients with Coronary-Artery Disease. https://app.cochat.ai/papers/10.1056/nejm197704142961503
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Borer, J. S., Bacharach, S. L., Green, M. V., Kent, K. M., Epstein, S. E., Johnston, G. S., & Mack, B. (1977). Real-Time Radionuclide Cineangiography in the Noninvasive Evaluation of Global and Regional Left Ventricular Function at Rest and during Exercise in Patients with Coronary-Artery Disease. New England Journal of Medicine. https://doi.org/10.1056/nejm197704142961503

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.