The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Cyclophosphamide Therapy of Severe Systemic Necrotizing Vasculitis
Abstract
We studied 17 patients with severe systemic necrotizing vasculitis over an 11-year-period. Sixteen patients were treated daily with cyclophosphamide (2 mg per kilogram per day), and one was treated with azathioprine (2 mg per kilogram per day). Before entering the study, all patients had active and progressive disease, even though 16 patients had been receiving corticosteroids that had caused severe and often incapacitating toxic side effects. Three patients died during the study. Complete and often dramatic remissions occurred in the surviving 14 patients, who were then placed on alternate-day corticosteroid treatment with continuation of cyclophosphamide. Corticosteroids were later discontinued in seven patients. The mean duration of remission was 22 months (range, two to 61). No patient showed recurrence of disease during treatment with cytotoxic agents.
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Citations
Cites
Allergic granulomatosis, allergic angiitis, and periarteritis nodosa.
Churg, J., & Strauss, L. (1951) · PubMed · Cited by 1,696
The Spectrum of Vasculitis: Clinical, Pathologic, Immunologic, and Therapeutic Considerations
FAUCI, A. S., HAYNES, B. F., & KATZ, P. (1978) · Annals of Internal Medicine · doi:10.7326/0003-4819-89-5-660 · Cited by 1,196
Self-citationWEGENERʼS GRANULOMATOSIS: STUDIES IN EIGHTEEN PATIENTS AND A REVIEW OF THE LITERATURE
FAUCI, A. S., & WOLFF, S. M. (1973) · Medicine · doi:10.1097/00005792-197311000-00002 · Cited by 788
Self-citationLong-term follow-up study of periarteritis nodosa
Frohnert, P. P., & Sheps, S. G. (1967) · The American Journal of Medicine · doi:10.1016/0002-9343(67)90144-1 · Cited by 456
VASCULITIS WITH HEPATITIS B ANTIGENEMIA: Long-term Observations in Nine Patients
SERGENT, J. S., LOCKSHIN, M. D., CHRISTIAN, C. L., & GOCKE, D. J. (1976) · Medicine · doi:10.1097/00005792-197601000-00001 · Cited by 278
Cyclophosphamide-induced remissions in advanced polyarteritis nodosa
Fauci, A. S., Doppman, J. L., & Wolff, S. M. (1978) · The American Journal of Medicine · doi:10.1016/0002-9343(78)90533-8 · Cited by 123
Self-citationReza, M. J., Dornfeld, L., Goldberg, L. S., et al. (1975) · Arthritis & Rheumatism · doi:10.1002/art.1780180513 · Cited by 103
Cited by
Rituximab versus Cyclophosphamide in ANCA-Associated Renal Vasculitis
Jones, R. B., Cohen Tervaert, J. W., Hauser, T., Luqmani, R., Morgan, M. D., Peh, C. A., Savage, C. O., Segelmark, M., Tesar, V., van Paassen, P., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0909169 · Cited by 1,748
Jayne, D., Rasmussen, N., Andrassy, K., Bacon, P., Tervaert, J. W. C., Dadoniené, J., Ekstrand, A., Gaskin, G., Gregorini, G., de Groot, K., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa020286 · Cited by 1,348
Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis
Jayne, D. R. W., Bruchfeld, A. N., Harper, L., Schaier, M., Venning, M. C., Hamilton, P., Burst, V., Grundmann, F., Jadoul, M., Szombati, I., et al. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2016111179 · Cited by 607
Gayraud, M., Guillevin, L., Le Toumelin, P., Cohen, P., Lhote, F., Casassus, P., Jarrousse, B., & the French Vasculitis Study Group (2001) · Arthritis & Rheumatism · doi:10.1002/1529-0131(200103)44:3<666::aid-anr116>3.0.co;2-a · Cited by 553
Noth, I., Strek, M. E., & Leff, A. R. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12518-4 · Cited by 527
Metadata
- Authors
- Fauci, A. S., Katz, P., Haynes, B. F., & Wolff, S. M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1979-08-02
- Volume
- 301
- Issue
- 5
- Pages
- 235-238
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2312254946
- Cited by
- 526
- References
- 7
- FWCI
- 29.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fauci, A. S., Katz, P., Haynes, B. F., & Wolff, S. M. (1979). Cyclophosphamide Therapy of Severe Systemic Necrotizing Vasculitis. New England Journal of Medicine. https://doi.org/10.1056/nejm197908023010503
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
