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Cited by 346

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Further Evidence Relating Mitral-Valve Prolapse to Cerebral Ischemic Events

Barnett, Henry J. M., Boughner, Derek R., Taylor, D. Wayne, Cooper, Paul E., Kostuk, William J., Nichol, Peter M.·1980·New England Journal of Medicine

Abstract

Echocardiography demonstrates prolapse of the mitral valve in at least 5 per cent of the population. Since some observations have linked this condition to stroke, we studied its incidence in two groups of patients with cerebral ischemia. The older group contained 141 patients over 45 years of age (mean, 64.7 years) who had transient ischemia or partial stroke. Prolapse was found in eight (5.7 per cent) of these patients and in 10 (7.1 per cent) of 141 age-matched controls. The second group contained 60 patients who had transient ischemia or partial stroke and were under 45 years old (mean 33.9 years). Prolapse was detected in 24 patients (40 per cent) but in only five (6.8 per cent) of 60 age-matched controls (mean age, 33.7 years). The odds ratio, 9.33, was highly significant (P less than 0.001). In six of the 24 patients there were other potential causes for cerebral ischemia leaving 18 whom the only recognizable potential cause was a prolapsing mitral valve (odds ratio, 7.00; P less than 0.001). This study suggests that this entity has a role in cerebral ischemia, at least in younger patients. (N Engl J Med 302:139-144, 1980).

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Metadata

Authors
Barnett, H. J. M., Boughner, D. R., Taylor, D. W., Cooper, P. E., Kostuk, W. J., & Nichol, P. M.
Venue
New England Journal of Medicine
Published
1980-01-17
Volume
302
Issue
3
Pages
139-144
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2335925017
Cited by
346
References
13
FWCI
15.83
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Further Evidence Relating Mitral-Valve Prolapse to Cerebral Ischemic Events. https://app.cochat.ai/papers/10.1056/nejm198001173020303
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Barnett, H. J. M., Boughner, D. R., Taylor, D. W., Cooper, P. E., Kostuk, W. J., & Nichol, P. M. (1980). Further Evidence Relating Mitral-Valve Prolapse to Cerebral Ischemic Events. New England Journal of Medicine. https://doi.org/10.1056/nejm198001173020303

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