The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Effects of Pregnancy and Contraceptive Steroids on Gallbladder Function
Abstract
We used real-time ultrasonography to study gallbladder kinetics in 11 nonpregnant women, 17 women using steroid contraceptives, and 33 pregnant women. Gallbladder volume was determined after an overnight fast and serially for 90 minutes after a standard liquid meal. After the first trimester of pregnancy, gallbladder volume during fasting and residual volume after contraction were twice as large as in control subjects. The rate of emptying and the percentage emptied were reduced. In early pregnancy the only important abnormality was a 30 per cent decrease in emptying rate. Gallbladder function was not affected by contraceptive steroids. Incomplete empyting of the gallbladder in late pregnancy leaves a large residual volume and may cause retention of cholesterol crystals, a prerequisite for cholesterol-gallstone formation. These findings are consistent with the view that pregnancy increases the risk of cholesterol gallstones. The increased incidence of gallstones associated with contraceptive steroids does not involve abnormal gallbladder kinetics.
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Cites
The epidemiology of gallbladder disease: Observations in the Framingham study
Friedman, G. D., Kannel, W. B., & Dawber, T. R. (1966) · Journal of Chronic Diseases · doi:10.1016/0021-9681(66)90132-9 · Cited by 523
Risk Factors for the Development of Cholelithiasis in Man: (First of Two Parts)
Bennion, L. J., & Grundy, S. M. (1978) · New England Journal of Medicine · doi:10.1056/nejm197811232992104 · Cited by 372
Davis, R. A., Kern, F., Showalter, R., Sutherland, E., Sinensky, M., & Simon, F. R. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.9.4130 · Cited by 198
Self-citationPertsemlidis, D., Panveliwalla, D., & Ahrens, E. H. (1974) · Gastroenterology · doi:10.1016/s0016-5085(74)80045-4 · Cited by 177
The role of the gallbladder in the pathogenesis of cholesterol gallstones
LaMorte, W. W., Schoetz, D. J., Birkett, D. H., & Williams, L. F. (1979) · Gastroenterology · doi:10.1016/0016-5085(79)90027-1 · Cited by 138
Nocturnal gallbladder storage and emptying in gallstone patients and healthy subjects
Henegouwen, G. P. V. B., & Hofmann, A. F. (1978) · Gastroenterology · doi:10.1016/0016-5085(78)90474-2 · Cited by 114
Effect of estrogens on the liver
Kern, F., Erfling, W., Simon, F. R., et al. (1978) · Gastroenterology · doi:10.1016/0016-5085(78)90860-0 · Cited by 63
Self-citationRole of gallbladder emptying and small bowel transit in regulation of bile acid pool size in man.
Duane, W. C., & Hanson, K. C. (1978) · PubMed · Cited by 41
Cited by
Does total parenteral nutrition induce gallbladder sludge formation and lithiasis?
Messing, B., Bories, C., Kunstlinger, F., & Bernier, J.-J. (1983) · Gastroenterology · doi:10.1016/0016-5085(83)90204-4 · Cited by 393
Abduljalil, K., Furness, P., Johnson, T. N., Rostami-Hodjegan, A., & Soltani, H. (2012) · Clinical Pharmacokinetics · doi:10.2165/11597440-000000000-00000 · Cited by 371
Sonographic measurement of gallbladder volume
Dodds, W., Groh, W., Darweesh, R., Lawson, T., Kishk, S., & Kern, M. (1985) · American Journal of Roentgenology · doi:10.2214/ajr.145.5.1009 · Cited by 320
Incidence, natural history, and risk factors for biliary sludge and stones during pregnancy†
Ko, C. W., Beresford, S. A. A., Schulte, S. J., Matsumoto, A. M., & Lee, S. P. (2005) · Hepatology · doi:10.1002/hep.20534 · Cited by 255
Metadata
- Authors
- Braverman, D. Z., Johnson, M. L., & Kern, F.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1980-02-14
- Volume
- 302
- Issue
- 7
- Pages
- 362-364
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2009183838
- Cited by
- 321
- References
- 8
- FWCI
- 20.81
- Type
- journal article
- Language
- en
- Open access
- closed
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- Braverman, D. Z., Johnson, M. L., & Kern, F. (1980). Effects of Pregnancy and Contraceptive Steroids on Gallbladder Function. New England Journal of Medicine. https://doi.org/10.1056/nejm198002143020702
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
