The DOI matches its Crossref record.
Complement-Induced Granulocyte Aggregation: An Unsuspected Mechanism of Disease
Abstract
The capacity of blood cells to aggregate, best exemplified by the response of platelets to vascular injury, is generally thought to be beneficial. However, if aggregation occurs inappropriately—that is, in a manner irrelevant to hemostasis — ischemic syndromes may result. The myocardial ischemia of Prinzmetal's angina pectoris, for example, may reflect platelet aggregation in coronary arteries. This article presents evidence that granulocytes as well as platelets can aggregate intravascularly, and that the resultant and previously unsuspected phenomenon of leukoembolization may underlie tissue damage in such diverse clinical situations as pulmonary dysfunction in hemodialyzed patients, sudden blindness with retinal infarction after . . .
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Citations
Cited by
Mullane, K. M., Kraemer, R., & Smith, B. (1985) · Journal of Pharmacological Methods · doi:10.1016/0160-5402(85)90029-4 · Cited by 992
Role of Free Radicals in Aging and Disease
HARMAN, D. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb27444.x · Cited by 262
Structure and function of the anaphylatoxins
Hugh, T. E. (1984) · Springer Seminars in Immunopathology · doi:10.1007/bf01893020 · Cited by 259
Intraocular Candidiasis in Patients with Candidemia
Donahue, S. P., Greven, C. M., Zuravleff, J. J., Eller, A. W., Nguyen, M. H., Peacock, J. E., Wagener, M. M., & Yu, V. L. (1994) · Ophthalmology · doi:10.1016/s0161-6420(94)31175-4 · Cited by 239
Metadata
- Authors
- Bleich, H. L., Moore, M. J., Jacob, H. S., Craddock, P. R., Hammerschmidt, D. E., & Moldow, C. F.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1980-04-03
- Volume
- 302
- Issue
- 14
- Pages
- 789-794
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2090763136
- Cited by
- 507
- References
- 0
- FWCI
- 15.16
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Complement-Induced Granulocyte Aggregation: An Unsuspected Mechanism of Disease. https://app.cochat.ai/papers/10.1056/nejm198004033021407
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- Bleich, H. L., Moore, M. J., Jacob, H. S., Craddock, P. R., Hammerschmidt, D. E., & Moldow, C. F. (1980). Complement-Induced Granulocyte Aggregation: An Unsuspected Mechanism of Disease. New England Journal of Medicine. https://doi.org/10.1056/nejm198004033021407
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
