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Nocturnal Asthma and Changes in Circulating Epinephrine, Histamine, and Cortisol
Abstract
NOCTURNAL and early morning wheezing is very common in asthmatics, 13 but the mechanisms are far from clear. The clinical importance of this symptom is underlined by the fact that many sudden deaths from asthma and many episodes of ventilatory arrest occur in the early morning.4 , 5 Several mechanisms have been proposed to explain nocturnal wheezing. There is little evidence that allergic factors such as house-dust mites in bedding have a major role, 6 and the same pattern of airway obstruction is observed in patients with nonatopic (intrinsic) asthma.3 Neither the supine posture nor sleep patterns appear to be important, and sleeping itself . . .
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Citations
Cited by
Asthma: From Bronchoconstriction to Airways Inflammation and Remodeling
BOUSQUET, J., JEFFERY, P. K., BUSSE, W. W., JOHNSON, M., & VIGNOLA, A. M. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.5.9903102 · Cited by 1,702
Cytokine Dysregulation, Inflammation and Well-Being
Elenkov, I. J., Iezzoni, D. G., Daly, A., Harris, A. G., & Chrousos, G. P. (2005) · Neuroimmunomodulation · doi:10.1159/000087104 · Cited by 502
Circadian disruption and human health
Fishbein, A. B., Knutson, K. L., & Zee, P. C. (2021) · Journal of Clinical Investigation · doi:10.1172/jci148286 · Cited by 468
Individual differences in the diurnal cycle of cortisol
Smyth, J. M., Ockenfels, M. C., Gorin, A. A., Catley, D., Porter, L. S., Kirschbaum, C., Hellhammer, D. H., & Stone, A. A. (1997) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(96)00039-x · Cited by 350
Mediators of immediate hypersensitivity
Wasserman, S. I. (1983) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(83)90512-2 · Cited by 288
Metadata
- Authors
- Barnes, P., FitzGerald, G., Brown, M., & Dollery, C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1980-07-31
- Volume
- 303
- Issue
- 5
- Pages
- 263-267
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2032992259
- Cited by
- 426
- References
- 0
- FWCI
- 15.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nocturnal Asthma and Changes in Circulating Epinephrine, Histamine, and Cortisol. https://app.cochat.ai/papers/10.1056/nejm198007313030506
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- Barnes, P., FitzGerald, G., Brown, M., & Dollery, C. (1980). Nocturnal Asthma and Changes in Circulating Epinephrine, Histamine, and Cortisol. New England Journal of Medicine. https://doi.org/10.1056/nejm198007313030506
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
