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Cited by 258

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Herpes Simplex Virus Proctitis in Homosexual Men: Clinical, Sigmoidoscopic, and Histopathological Features

Goodell, Steven E., Quinn, Thomas C., Mkrtichian, Emmanuel, Schuffler, Michael D., Holmes, King K., Corey, Lawrence·1983·New England Journal of Medicine

Abstract

Acute herpes simplex virus (HSV) infection was detected in 23 of 102 consecutively examined, sexually active male homosexuals who presented with anorectal pain, discharge, tenesmus, or hematochezia, as compared with 3 of 75 homosexual men without gastrointestinal symptoms (P less than 0.01). Findings that were significantly more frequent in men with HSV proctitis than in men with proctitis due to other infectious causes included fever (48 per cent), difficulty in urinating (48 per cent), sacral paresthesias (26 per cent), inguinal lymphadenopathy (57 per cent), severe anorectal pain (100 per cent), tenesmus (100 per cent), constipation (78 per cent), perianal ulcerations (70 per cent), and the presence of diffuse ulcerative or discrete vesicular or pustular lesions in the distal 5 cm of the rectum (50 per cent). Serologic evidence indicated that 85 per cent of the men with symptomatic HSV proctitis were having their first episode of HSV-2 infection. The diagnosis of HSV proctitis is suggested by the presence of severe anorectal pain, difficulty in urinating, sacral paresthesias or pain, and diffuse ulceration of the distal rectal mucosa.

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Metadata

Authors
Goodell, S. E., Quinn, T. C., Mkrtichian, E., Schuffler, M. D., Holmes, K. K., & Corey, L.
Venue
New England Journal of Medicine
Published
1983-04-14
Volume
308
Issue
15
Pages
868-871
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2338779222
Cited by
258
References
11
FWCI
14.36
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Herpes Simplex Virus Proctitis in Homosexual Men: Clinical, Sigmoidoscopic, and Histopathological Features. https://app.cochat.ai/papers/10.1056/nejm198304143081503
The paper
Goodell, S. E., Quinn, T. C., Mkrtichian, E., Schuffler, M. D., Holmes, K. K., & Corey, L. (1983). Herpes Simplex Virus Proctitis in Homosexual Men: Clinical, Sigmoidoscopic, and Histopathological Features. New England Journal of Medicine. https://doi.org/10.1056/nejm198304143081503

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