The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Western Washington Randomized Trial of Intracoronary Streptokinase in Acute Myocardial Infarction
Abstract
Two hundred fifty patients were enrolled in a multicenter, community-based study of the efficacy of intracoronary streptokinase thrombolysis in acute myocardial infarction; 134 were randomly assigned to streptokinase therapy and 116 were controls. All patients underwent left ventricular angiography and coronary arteriography before the random assignment. The mean time from the onset of symptoms to hospitalization was 134 +/- 144 minutes (S.D), and the mean time to random assignment was 276 +/- 185 minutes. Coronary reperfusion was achieved in 68 per cent of the streptokinase-treated group. The overall 30-day mortality was 18 (7.2 per cent); there were five deaths in the streptokinase-treated group (3.7 per cent) and 13 in the control group (11.2 per cent, P less than 0.02). Fifteen of the 18 deaths occurred in patients with anterior infarction. Intracoronary streptokinase therapy resulted in a nearly threefold reduction in the 30-day mortality after hospitalization for acute myocardial infarction.
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Cites
Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction
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Intracoronary thrombolysis in evolving myocardial infarction
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A Randomized Trial of Intracoronary Streptokinase in the Treatment of Acute Myocardial Infarction
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Cited by
Protein Therapeutics: A Summary and Pharmacological Classification
Leader, B., Baca, Q. J., & Golan, D. E. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2399 · Cited by 2,161
Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour
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IMPROVED SURVIVAL AFTER EARLY THROMBOLYSIS IN ACUTE MYOCARDIAL INFARCTION
Simoons, M. L., Brand, M. V., Zwaan, C. D., Verheugt, F. W. A., Remme, W. J., Serruys, P. W., Bär, F., Res, J., Krauss, X. H., Vermeer, F., et al. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90584-7 · Cited by 451
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Metadata
- Authors
- Kennedy, J. W., Ritchie, J. L., Davis, K. B., & Fritz, J. K.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1983-12-15
- Volume
- 309
- Issue
- 24
- Pages
- 1477-1482
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2318123143
- Cited by
- 788
- References
- 11
- FWCI
- 55.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kennedy, J. W., Ritchie, J. L., Davis, K. B., & Fritz, J. K. (1983). Western Washington Randomized Trial of Intracoronary Streptokinase in Acute Myocardial Infarction. New England Journal of Medicine. https://doi.org/10.1056/nejm198312153092402
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
