The DOI matches its Crossref record.
Risk of Nosocomial Infection with Human T-Cell Lymphotropic Virus III (HTLV-III)
Abstract
Infection with human T-cell lymphotropic virus III (HTLV-III) is closely linked to the acquired immunodeficiency syndrome (AIDS). We evaluated the risk of nosocomial infection with HTLV-III by testing for antibodies to HTLV-III among hospital employees, including victims of needle-stick exposure, endoscopists, pathologists, and laboratory workers. Assays for antibody against the virus were performed by enzyme-linked immunosorbent assay and electrophoretic (Western blot) techniques. Although all 22 of our patients with AIDS and 6 of 7 with AIDS-related complex were found to have antibodies to HTLV-III when both assays were employed, none of the 85 employees with nosocomial exposure to specimens from patients with AIDS were positive for HTLV-III antibody. These studies must be regarded as preliminary, but they suggest that when current hospital isolation procedures are employed, the risk of nosocomial transmission of HTLV-III is low.
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Citations
Cited by
Ippolito, G. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.1993.00410120035005 · Cited by 355
Cultural Practices Contributing to the Transmission of Human Immunodeficiency Virus in Africa
Hrdy, D. B. (1987) · Clinical Infectious Diseases · doi:10.1093/clinids/9.6.1109 · Cited by 157
Metadata
- Authors
- Hirsch, M. S., Wormser, G. P., Schooley, R. T., Ho, D. D., Felsenstein, D., Hopkins, C. C., Joline, C., Duncanson, F., Sarngadharan, M. G., Saxinger, C., & Gallo, R. C.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1985-01-03
- Volume
- 312
- Issue
- 1
- Pages
- 1-4
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2036775666
- Cited by
- 207
- References
- 0
- FWCI
- 53.64
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Risk of Nosocomial Infection with Human T-Cell Lymphotropic Virus III (HTLV-III). https://app.cochat.ai/papers/10.1056/nejm198501033120101
- The paper
- Hirsch, M. S., Wormser, G. P., Schooley, R. T., Ho, D. D., Felsenstein, D., Hopkins, C. C., Joline, C., Duncanson, F., Sarngadharan, M. G., Saxinger, C., & Gallo, R. C. (1985). Risk of Nosocomial Infection with Human T-Cell Lymphotropic Virus III (HTLV-III). New England Journal of Medicine. https://doi.org/10.1056/nejm198501033120101
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
