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Use of the Initial Electrocardiogram to Predict In-Hospital Complications of Acute Myocardial Infarction

Brush, John E., Brand, Donald A., Acampora, Denise, Chalmer, Bruce, Wackers, Frans J.·1985·New England Journal of Medicine

Abstract

We evaluated the initial electrocardiogram as a predictor of complications in 469 patients with suspected acute myocardial infarction. An electrocardiogram was classified as positive if it showed one or more of the following: evidence of infarction, ischemia, or strain; left ventricular hypertrophy; left bundle-branch block; or paced rhythm. Forty-two (14 per cent) of 302 patients with positive electrocardiograms had at least one life-threatening complication (ventricular fibrillation, sustained ventricular tachycardia, or heart block), as compared with 1 (0.6 per cent) of 167 patients with a negative electrocardiogram. Life-threatening complications were therefore 23 times more likely if the initial electrocardiogram was positive (P less than 0.001). Other complications were 3 to 10 times more likely (P less than 0.01), interventions were 4 to 10 times more likely (P less than 0.05), and death was 17 times more likely (P less than 0.001) in patients with a positive electrocardiogram. We conclude that patients with a negative initial electrocardiogram have a low likelihood of complications and could be admitted to an intermediate care unit instead of a coronary care unit. This would reduce admissions to the coronary care unit by 36 per cent and thereby save considerable hospital costs without compromising patient care.

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Metadata

Authors
Brush, J. E., Brand, D. A., Acampora, D., Chalmer, B., & Wackers, F. J.
Venue
New England Journal of Medicine
Published
1985-05-02
Volume
312
Issue
18
Pages
1137-1141
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2317193860
Cited by
352
References
0
FWCI
10.39
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Use of the Initial Electrocardiogram to Predict In-Hospital Complications of Acute Myocardial Infarction. https://app.cochat.ai/papers/10.1056/nejm198505023121801
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Brush, J. E., Brand, D. A., Acampora, D., Chalmer, B., & Wackers, F. J. (1985). Use of the Initial Electrocardiogram to Predict In-Hospital Complications of Acute Myocardial Infarction. New England Journal of Medicine. https://doi.org/10.1056/nejm198505023121801

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.