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Anaphylactic Reactions after Gamma Globulin Administration in Patients with Hypogammaglobulinemia
Abstract
VYAS and co-workers1 were the first to identify anti-IgA antibodies as the cause of anaphylactic reactions to human blood products in patients with selective IgA deficiency. Other reports of anaphylaxis due to anti-IgA antibodies soon followed,2 3 4 5 6 7 8 9 10 11 12 13 including several reports of anaphylactic reactions in patients with common variable immunodeficiency.3 4 5 6 7 8 , 11 Although such patients have severe defects in antibody production, they often retain the ability to produce autoantibodies. Gamma globulin replacement is essential in the management of hypogammaglobulinemia,6 in contrast to selective IgA deficiency. Therefore, it is important to find ways to circumvent these life-threatening anaphylactic reactions and to provide adequate replacement therapy. . . .
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Cited by
Ochs, H. D., Gupta, S., Kiessling, P., Nicolay, U., Berger, M., & the Subcutaneous IgG Study Group (2006) · Journal of Clinical Immunology · doi:10.1007/s10875-006-9021-7 · Cited by 260
Vultaggio, A., Azzari, C., Milito, C., Finocchi, A., Toppino, C., Spadaro, G., Trizzino, A., Baldassarre, M., Paganelli, R., Moschese, V., et al. (2015) · Clinical Drug Investigation · doi:10.1007/s40261-015-0270-1 · Cited by 58
Metadata
- Authors
- Burks, A. W., Sampson, H. A., & Buckley, R. H.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1986-02-27
- Volume
- 314
- Issue
- 9
- Pages
- 560-564
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2026228148
- Cited by
- 325
- References
- 0
- FWCI
- 4.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Anaphylactic Reactions after Gamma Globulin Administration in Patients with Hypogammaglobulinemia. https://app.cochat.ai/papers/10.1056/nejm198602273140907
- The paper
- Burks, A. W., Sampson, H. A., & Buckley, R. H. (1986). Anaphylactic Reactions after Gamma Globulin Administration in Patients with Hypogammaglobulinemia. New England Journal of Medicine. https://doi.org/10.1056/nejm198602273140907
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
