The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Oncogenes and Tumor-Suppressing Genes
Abstract
THE past decade has witnessed great changes in our understanding of the molecular origins of cancer. Much of this progress stems from the discovery of specific genes, the oncogenes, which are carried in the genomes of a variety of tumor cells and appear to be responsible for specifying many of the malignant traits of these cells. Laboratory work in several areas has now uncovered 30 distinct oncogenes, some of which are associated with specific tumor types.1 Recently, researchers have discovered a very different class of genes that are involved in some forms of carcinogenesis. These "tumor-suppressing" genes appear to be . . .
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Citations
Cites
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
Friend, S. H., Bernards, R., Rogelj, S., Weinberg, R. A., Rapaport, J. M., Albert, D. M., & Dryja, T. P. (1986) · Nature · doi:10.1038/323643a0 · Cited by 2,948
Self-citation
Cited by
Thompson, L., Chang, B., & Barsky, S. H. (1996) · The American Journal of Surgical Pathology · doi:10.1097/00000478-199603000-00003 · Cited by 365
Novel putative receptor tyrosine kinase encoded by the melanoma-inducing Tu locus in Xiphophorus
Wittbrodt, J., Adam, D., Malitschek, B., Mäueler, W., Raulf, F., Telling, A., Robertson, S. M., & Schartl, M. (1989) · Nature · doi:10.1038/341415a0 · Cited by 337
Metadata
- Authors
- Flier, J. S., Underhill, L. H., Friend, S. H., Dryja, T. P., & Weinberg, R. A.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1988-03-10
- Volume
- 318
- Issue
- 10
- Pages
- 618-622
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W1984816214
- Cited by
- 217
- References
- 1
- FWCI
- 19.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Flier, J. S., Underhill, L. H., Friend, S. H., Dryja, T. P., & Weinberg, R. A. (1988). Oncogenes and Tumor-Suppressing Genes. New England Journal of Medicine. https://doi.org/10.1056/nejm198803103181007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
