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Cited by 297

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Weight, Diet, and the Risk of Symptomatic Gallstones in Middle-Aged Women

Maclure, K. Malcolm, Hayes, K.C., Colditz, Graham A., Stampfer, Meir J., Speizer, Frank E., Willett, Walter C.·1989·New England Journal of Medicine
DOI 10.1056/nejm198908313210902
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Abstract

To assess the risk factors for symptomatic gallstones, 88,837 women in the Nurses' Health Study cohort (age range, 34 to 59 years) were followed for four years after completing a detailed questionnaire about food and alcohol intake in 1980. A total of 433 cholecystectomies and 179 cases of newly symptomatic, unremoved gallstones, diagnosed by ultrasonographic examination or x-ray films, were reported during the four-year follow-up. The age-adjusted relative risk for very obese women, who had a Quetelet index of relative weight (weight in kilograms divided by the square of the height in meters) of more than 32 kg per square meter, was 6.0 (95 percent confidence interval, 4.0 to 9.0), as compared with women whose relative weight was less than 20 kg per square meter. For slightly overweight women (relative weight, 24 to 24.9 kg per square meter), the relative risk was 1.7 (95 percent confidence interval, 1.1 to 2.7). Overall, we observed a roughly linear relation between relative weight and the risk of gallstones. Among the 59,306 women whose relative weight was less than 25 kg per square meter, a high energy intake (greater than 8200 J per day), as compared with a low energy intake (less than 4730 J per day), was associated with an increased incidence of symptomatic gallstones (relative risk, 2.1; 95 percent confidence interval, 1.4 to 3.3), and an alcohol intake of at least 5 g per day was associated with a decreased incidence as compared with abstention (relative risk, 0.6; 9…

Overview

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Registry

Crossref · 10.1056/nejm198908313210902

Cites

1 of 1 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Increased body fat is lithogenic, and higher body weight is associated with greater risk of cholesterol stones in the gallbladder.

    “Thus, increased body fat is lithogenic [19], and the higher the body weight, the greater the risk of cholesterol stones in the gallbladder [12].”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [12]

  • Both obesity and abdominal obesity increase the risk of stone formation and of requiring cholecystectomy because of higher likelihood of symptomatic stones.

    “Both obesity and abdominal obesity increase the risk not only of stone formation but also of requiring surgical treatment (cholecystectomy) because of the higher likelihood of presenting with symptomatic stones [10,12,13].”

    From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [12]

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 36

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Metadata

Authors
Maclure, K. M., Hayes, K. C., Colditz, G. A., Stampfer, M. J., Speizer, F. E., & Willett, W. C.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1989-08-31
Volume
321
Issue
9
Pages
563-569
ISSN
  • 0028-4793
  • 1533-4406
DOI
10.1056/nejm198908313210902
Cited by
297
References
1
Language
en

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