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Cited by 313

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

The Use of Intravenous Immune Globulin in Immunodeficiency Diseases

Oates, John A., Wood, Alastair J.J., Buckley, Rebecca H., Schiff, Richard I.·1991·New England Journal of Medicine

Abstract

WITH the discovery of agammaglobulinemia in 1952,1 a pressing need emerged for antibody-replacement therapy to prevent serious bacterial infections. Intramuscularly administered immune serum globulin resulted in a remarkable decrease in the incidence of such infections in patients with this type of immunodeficiency; however, the injections were painful, and the IgG was absorbed slowly and was subject to local proteolysis. Intravenous administration of immune serum globulin resulted in shocklike episodes, chills, and hyperpyrexia, especially in sick and acutely infected children. Beginning in the early 1960s, many attempts were made to modify immune serum globulin so that it could be given safely . . .

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Crossref · 10.1056/nejm199107113250207

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Metadata

Authors
Oates, J. A., Wood, A. J. J., Buckley, R. H., & Schiff, R. I.
Venue
New England Journal of Medicine
Published
1991-07-11
Volume
325
Issue
2
Pages
110-117
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2336504859
Cited by
313
References
1
FWCI
8.69
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Use of Intravenous Immune Globulin in Immunodeficiency Diseases. https://app.cochat.ai/papers/10.1056/nejm199107113250207
The paper
Oates, J. A., Wood, A. J. J., Buckley, R. H., & Schiff, R. I. (1991). The Use of Intravenous Immune Globulin in Immunodeficiency Diseases. New England Journal of Medicine. https://doi.org/10.1056/nejm199107113250207

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.