The DOI matches its Crossref record.
Prognostic Factors and Treatment Decisions in Axillary-Node-Negative Breast Cancer
Abstract
Approximately 186,000 new cases of breast cancer will occur in the United States in 1992, and about two thirds of these cases will not involve axillary nodes. This means that each month decisions about adjuvant therapy will be made for more than 10,000 patients with node-negative breast cancer.Why not simply treat all patients with node-negative breast cancer with additional systemic therapy?1 , 2 One should not, for the following reasons. First, approximately 70 percent of such patients are cured without any adjuvant therapy. Thus, a large number of women without disease would be subjected to the toxic effects of this therapy . . .
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Citations
Cited by
Breast cancer metastasis: markers and models
Weigelt, B., Peterse, J. L., & van't Veer, L. J. (2005) · Nature Reviews Cancer · doi:10.1038/nrc1670 · Cited by 2,232
Primary node negative breast cancer in BRCA1 mutation carriers has a poor outcome
Foulkes, W. D., Chappuis, P. O., Wong, N., Brunet, J.-S., Vesprini, D., Rozen, F., Yuan, Z. Q., Pollak, M. N., Kuperstein, G., Narod, S. A., et al. (2000) · Annals of Oncology · doi:10.1023/a:1008340723974 · Cited by 86
Metadata
- Authors
- Desforges, J. F., McGuire, W. L., & Clark, G. M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1992-06-25
- Volume
- 326
- Issue
- 26
- Pages
- 1756-1761
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4238806036
- Cited by
- 282
- References
- 0
- FWCI
- 15.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Prognostic Factors and Treatment Decisions in Axillary-Node-Negative Breast Cancer. https://app.cochat.ai/papers/10.1056/nejm199206253262607
- The paper
- Desforges, J. F., McGuire, W. L., & Clark, G. M. (1992). Prognostic Factors and Treatment Decisions in Axillary-Node-Negative Breast Cancer. New England Journal of Medicine. https://doi.org/10.1056/nejm199206253262607
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.