The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Mifepristone (RU 486) -- A Modulator of Progestin and Glucocorticoid Action
Abstract
Antiprogestins, agents that inhibit the action of progesterone, are among the most controversial and yet the more interesting therapeutic compounds developed in the past 20 years. These agents provide the most effective and safest means of medical abortion, and in addition they may be used for the treatment of patients with cancer, Cushing's syndrome, and gynecologic disorders and for contraception. The first effective antiprogestin was mifepristone (also known as RU 486),1 a derivative of the progestin norethindrone (Figure 1). By analogy with the antiestrogens, it is likely that the substitution at the 11 beta position is responsible for the antiprogestin . . .
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Cites
Kettel, L. M., Murphy, A. A., Mortola, J. F., Liu, J. H., Ulmann, A., & Yen, S. S. C. (1991) · Fertility and Sterility · doi:10.1016/s0015-0282(16)54531-2 · Cited by 151
LAUE, L., LOTZE, M. T., CHROUSOS, G. P., BARNES, K., LORIAUX, D. L., & FLEISHER, T. A. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-71-6-1474 · Cited by 77
Cited by
Early Pregnancy Termination with Mifepristone and Misoprostol in the United States
Spitz, I. M., Bardin, C. W., Benton, L., & Robbins, A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199804303381801 · Cited by 441
Self-citationStress-glucocorticoid-TSC22D3 axis compromises therapy-induced antitumor immunity
Yang, H., Xia, L., Chen, J., Zhang, S., Martin, V., Li, Q., Lin, S., Chen, J., Calmette, J., Lu, M., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0566-4 · Cited by 379
Direct Effect of Glucocorticoids on Lipolysis in Adipocytes
Xu, C., He, J., Jiang, H., Zu, L., Zhai, W., Pu, S., & Xu, G. (2009) · Molecular Endocrinology · doi:10.1210/me.2008-0464 · Cited by 291
Clinical and Biological Effects of Mifepristone Treatment for Psychotic Depression
Flores, B. H., Kenna, H., Keller, J., Solvason, H. B., & Schatzberg, A. F. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300884 · Cited by 203
The endocrinology of menstruation – a role for the immune system
Critchley, H. O. D., Kelly, R. W., Brenner, R. M., & Baird, D. T. (2001) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2001.01432.x · Cited by 203
Metadata
- Authors
- Wood, A. J. J., Spitz, I. M., & Bardin, C. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1993-08-05
- Volume
- 329
- Issue
- 6
- Pages
- 404-412
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2336040302
- Cited by
- 221
- References
- 2
- FWCI
- 12.61
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wood, A. J. J., Spitz, I. M., & Bardin, C. W. (1993). Mifepristone (RU 486) -- A Modulator of Progestin and Glucocorticoid Action. New England Journal of Medicine. https://doi.org/10.1056/nejm199308053290607
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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