The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Hemophilia A
Abstract
The dramatic hemorrhages, the effect of the disease on history through its presence in Queen Victoria's descendants, and the devastating role of therapeutic concentrates in the transmission of the acquired immunodeficiency syndrome (AIDS) have made hemophilia A the object of great medical, scientific, and public interest. The commonest hereditary coagulation disorder and a disease without ethnic or geographic limitations, its incidence approaches 20 per 100,000 male births13. John Conrad Otto emphasized its inheritance as an X-linked disorder in his 1803 description of the disease in a New Hampshire family: “males only are subject to this strong affection . . . .
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Characterization of the human factor VIII gene
Gitschier, J., Wood, W. I., Goralka, T. M., Wion, K. L., Chen, E. Y., Eaton, D. H., Vehar, G. A., Capon, D. J., & Lawn, R. M. (1984) · Nature · doi:10.1038/312326a0 · Cited by 988
Twenty‐five years' experience of prophylactic treatment in severe haemophilia A and B
NILSSON, I. M., BERNTORP, E., LÖFQVIST, T., & PETTERSSON, H. (1992) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.1992.tb00546.x · Cited by 961
Molecular cloning of a cDNA encoding human antihaemophilic factor
Toole, J. J., Knopf, J. L., Wozney, J. M., Sultzman, L. A., Buecker, J. L., Pittman, D. D., Kaufman, R. J., Brown, E., Shoemaker, C., Orr, E. C., et al. (1984) · Nature · doi:10.1038/312342a0 · Cited by 925
Structure of human factor VIII
Vehar, G. A., Keyt, B., Eaton, D., Rodriguez, H., O'Brien, D. P., Rotblat, F., Oppermann, H., Keck, R., Wood, W. I., Harkins, R. N., et al. (1984) · Nature · doi:10.1038/312337a0 · Cited by 883
Surface-dependent reactions of the vitamin K-dependent enzyme complexes
Mann, K., Nesheim, M., Church, W., Haley, P., & Krishnaswamy, S. (1990) · Blood · doi:10.1182/blood.v76.1.1.1 · Cited by 879
Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A
Lakich, D., Kazazian, H. H., Antonarakis, S. E., & Gitschier, J. (1993) · Nature Genetics · doi:10.1038/ng1193-236 · Cited by 788
Osterud, B., & Rapaport, S. I. (1977) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.74.12.5260 · Cited by 787
Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs
Ehrenforth, S., Kreuz, W., Linde, R., Funk, M., Güngor, T., Krackhardt, B., Kornhuber, B., & Scharrer, I. (1992) · The Lancet · doi:10.1016/0140-6736(92)90874-3 · Cited by 605
The role of phospholipid and factor VIIIa in the activation of bovine factor X.
DIEIJEN, G. V., Tans, G., Rosing, J., & Hemker, H. C. (1981) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)69627-4 · Cited by 584
Goedert, J. J., Kessler, C. M., Aledort, L. M., Biggar, R. J., Andes, W. A., White, G. C., Drummond, J. E., Vaidya, K., Mann, D. L., Eyster, M. E., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198910263211701 · Cited by 524
Cited by
The hemophilias--from royal genes to gene therapy
Mannucci, P. M., & Tuddenham, E. G. D. (2001) · New England Journal of Medicine · doi:10.1056/nejm200106073442307 · Cited by 1,110
Roach, E. S., Golomb, M. R., Adams, R., Biller, J., Daniels, S., deVeber, G., Ferriero, D., Jones, B. V., Kirkham, F. J., Scott, R. M., et al. (2008) · Stroke · doi:10.1161/strokeaha.108.189696 · Cited by 963
Zhang, A.-H., Rossi, R. J., Yoon, J., Wang, H., & Scott, D. W. (2016) · Cellular Immunology · doi:10.1016/j.cellimm.2015.11.004 · Cited by 65
Metadata
- Authors
- Hoyer, L. W.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1994-01-06
- Volume
- 330
- Issue
- 1
- Pages
- 38-47
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W4230915316
- Cited by
- 361
- References
- 63
- FWCI
- 7.13
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Hemophilia A. https://app.cochat.ai/papers/10.1056/nejm199401063300108
- The paper
- Hoyer, L. W. (1994). Hemophilia A. New England Journal of Medicine. https://doi.org/10.1056/nejm199401063300108
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
