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Fatal Encephalitis Due to Variant B Human Herpesvirus-6 Infection in a Bone Marrow-Transplant Recipient
Open accessAbstract
Human herpesvirus-6 (HHV-6) is the causative agent of exanthem subitum1 and febrile illnesses2 in children. More recently, HHV-6 has been shown to infect the recipients of bone marrow transplants and has been implicated in interstitial pneumonitis3,4 and bone marrow suppression5 after transplantation. The pathogenicity of HHV-6, however, has yet to be fully delineated in either immunocompetent or immunocompromised hosts. In some children with exanthem subitum, seizures, encephalopathy, and the detection of HHV-6 DNA in cerebrospinal fluid have provided circumstantial evidence that HHV-6 can infect the central nervous system6,7. Nevertheless, these studies have failed to document the direct . . .
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Citations
Cited by
CD46 Is a Cellular Receptor for Human Herpesvirus 6
Santoro, F., Kennedy, P. E., Locatelli, G., Malnati, M. S., Berger, E. A., & Lusso, P. (1999) · Cell · doi:10.1016/s0092-8674(00)81678-5 · Cited by 522
Molecular Methods for Diagnosis of Viral Encephalitis
DeBiasi, R. L., & Tyler, K. L. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.4.903-925.2004 · Cited by 274
Neuroimaging of herpesvirus infections in children
Baskin, H. J., & Hedlund, G. (2007) · Pediatric Radiology · doi:10.1007/s00247-007-0506-1 · Cited by 127
Exanthem Subitum-Associated Encephalitis: Nationwide Survey in Japan
Yoshikawa, T., Ohashi, M., Miyake, F., Fujita, A., Usui, C., Sugata, K., Suga, S., Hashimoto, S., & Asano, Y. (2009) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2009.05.012 · Cited by 82
Luppi, M., Barozzi, P., Maiorana, A., Marasca, R., Trovato, R., Fano, R., Ceccherini‐Nelli, L., & Torelli, G. (1995) · Journal of Medical Virology · doi:10.1002/jmv.1890470119 · Cited by 79
Metadata
- Authors
- Drobyski, W. R., Knox, K. K., Majewski, D., & Carrigan, D. R.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1994-05-12
- Volume
- 330
- Issue
- 19
- Pages
- 1356-1360
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2327671886
- Cited by
- 345
- References
- 0
- FWCI
- 17.06
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Fatal Encephalitis Due to Variant B Human Herpesvirus-6 Infection in a Bone Marrow-Transplant Recipient. https://app.cochat.ai/papers/10.1056/nejm199405123301905
- The paper
- Drobyski, W. R., Knox, K. K., Majewski, D., & Carrigan, D. R. (1994). Fatal Encephalitis Due to Variant B Human Herpesvirus-6 Infection in a Bone Marrow-Transplant Recipient. New England Journal of Medicine. https://doi.org/10.1056/nejm199405123301905
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
