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Cited by 754

The DOI matches its Crossref record.

Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine

Lefkovits, Jeffrey, Plow, Edward F., Topol, Eric J.·1995·New England Journal of Medicine
DOI 10.1056/nejm199506083322306
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Abstract

Platelets have a key role in atherosclerosis, thrombosis, and acute coronary syndromes. Therapeutic manipulation of platelet function has focused principally on the use of aspirin, which has proved effective in many clinical situations, despite its relatively weak antiplatelet action. More recently, the platelet glycoprotein IIb/IIIa receptor has been identified as the pivotal mediator of platelet aggregation, making it a logical target for control of the platelet response to vascular injury. This review summarizes the current state of knowledge of the biology of glycoprotein IIb/IIIa receptors and examines the development of agents that inhibit these receptors — a diverse group of . . .

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Metadata

Authors
Lefkovits, J., Plow, E. F., & Topol, E. J.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1995-06-08
Volume
332
Issue
23
Pages
1553-1559
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm199506083322306
OpenAlex
W2335477357
Cited by
754
References
0
FWCI
35.57
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine. https://app.cochat.ai/papers/10.1056/nejm199506083322306
The paper
Lefkovits, J., Plow, E. F., & Topol, E. J. (1995). Platelet Glycoprotein IIb/IIIa Receptors in Cardiovascular Medicine. New England Journal of Medicine. https://doi.org/10.1056/nejm199506083322306

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.