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Cited by 488

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Corticosteroid Therapy in Severe Illness

Open access
Lamberts, Steven W.J., Bruining, Hajo A., de Jong, Frank H.·1997·New England Journal of Medicine
DOI 10.1056/nejm199710303371807
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Abstract

Severe illnesses, trauma, anesthesia, and surgery are accompanied by activation of the hypothalamic–pituitary–adrenal axis, as demonstrated by increased serum corticotropin and cortisol concentrations.17 This activation is an essential component of the general adaptation to stress and contributes to the maintenance of homeostasis.8 The efficacy of replacement doses or high doses of corticosteroids in patients with severe illness, especially those with multiorgan-system diseases, is uncertain.912 The uncertainty is even greater in patients who are already taking corticosteroids. Standard therapy for the latter patients consists of the administration of high doses of corticosteroids during any severe illness and perioperatively. We . . .

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Crossref · 10.1056/nejm199710303371807

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Metadata

Authors
Lamberts, S. W. J., Bruining, H. A., & de Jong, F. H.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
1997-10-30
Volume
337
Issue
18
Pages
1285-1292
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejm199710303371807
OpenAlex
W2050583714
Cited by
488
References
11
FWCI
9.29
Type
journal article
Language
en
Open access
green

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.