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Thromboangiitis Obliterans (Buerger's Disease)

Olin, Jeffrey W.·2000·New England Journal of Medicine

Abstract

Thromboangiitis obliterans (Buerger's disease) is a nonatherosclerotic segmental inflammatory disease that most commonly affects the small and medium-sized arteries, veins, and nerves of the arms and legs.1 Von Winiwarter first described a patient with thromboangiitis obliterans in 1879.2 Twenty-nine years later, Leo Buerger provided a detailed and accurate description of the pathological findings in 11 amputated limbs.3 Thromboangiitis obliterans differs from other forms of vasculitis in some important ways. Pathologically, there is a highly cellular and inflammatory thrombus with relative sparing of the blood-vessel wall. The acute-phase reactants (as assessed by the Westergren sedimentation rate and serum C-reactive protein level) . . .

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Metadata

Authors
Olin, J. W.
Venue
New England Journal of Medicine
Published
2000-09-21
Volume
343
Issue
12
Pages
864-869
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W3109997177
Cited by
589
References
0
FWCI
12.88
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Thromboangiitis Obliterans (Buerger's Disease). https://app.cochat.ai/papers/10.1056/nejm200009213431207
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Olin, J. W. (2000). Thromboangiitis Obliterans (Buerger's Disease). New England Journal of Medicine. https://doi.org/10.1056/nejm200009213431207

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.