The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Is Liver Fibrosis Reversible?
Abstract
Cirrhosis represents a late stage of progressive scarring in chronic liver disease. It begins with subendothelial or pericentral fibrosis (hepatic fibrosis) and progresses to panlobular fibrosis with nodule formation (cirrhosis). Once established, fibrosis has generally been considered to be irreversible. This belief was established more than half a century ago, when the diagnosis of cirrhosis was made clinically on the basis of signs of end-stage liver disease, such as ascites, muscle wasting, variceal bleeding, jaundice, and encephalopathy. These features continue to indicate a poor prognosis in the absence of liver transplantation and are still used to classify the severity of . . .
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Citations
Cites
Iredale, J. P., Benyon, R. C., Pickering, J., McCullen, M., Northrop, M., Pawley, S., Hovell, C., & Arthur, M. J. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1018 · Cited by 1,075
Hammel, P., Couvelard, A., O'Toole, D., Ratouis, A., Sauvanet, A., Fléjou, J. F., Degott, C., Belghiti, J., Bernades, P., Valla, D., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102083440604 · Cited by 427
Cited by
Mechanisms of Hepatic Fibrogenesis
Friedman, S. L. (2008) · Gastroenterology · doi:10.1053/j.gastro.2008.03.003 · Cited by 2,634
Self-citationAla, A., Walker, A. P., Ashkan, K., Dooley, J. S., & Schilsky, M. L. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60196-2 · Cited by 1,446
The Use of Silymarin in the Treatment of Liver Diseases
Saller, R., Meier, R., & Brignoli, R. (2001) · Drugs · doi:10.2165/00003495-200161140-00003 · Cited by 718
Mechanisms of Disease: mechanisms of hepatic fibrosis and therapeutic implications
Friedman, S. L. (2004) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0055 · Cited by 498
Self-citationThe role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
Elsharkawy, A. M., Oakley, F., & Mann, D. A. (2005) · Apoptosis · doi:10.1007/s10495-005-1055-4 · Cited by 419
Metadata
- Authors
- Bonis, P. A. L., Friedman, S. L., & Kaplan, M. M.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2001-02-08
- Volume
- 344
- Issue
- 6
- Pages
- 452-454
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2046678597
- Cited by
- 174
- References
- 2
- FWCI
- 5.83
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bonis, P. A. L., Friedman, S. L., & Kaplan, M. M. (2001). Is Liver Fibrosis Reversible? New England Journal of Medicine. https://doi.org/10.1056/nejm200102083440610
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
