The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Effects of Estrogen plus Progestin on Health-Related Quality of Life
Open accessAbstract
BACKGROUND: The Women's Health Initiative (WHI) and other clinical trials indicate that significant health risks are associated with combination hormone use. Less is known about the effect of hormone therapy on health-related quality of life. METHODS: The WHI randomly assigned 16,608 postmenopausal women 50 to 79 years of age (mean, 63) with an intact uterus at base line to estrogen plus progestin (0.625 mg of conjugated equine estrogen plus 2.5 mg of medroxyprogesterone acetate, in 8506 women) or placebo (in 8102 women). Quality-of-life measures were collected at base line and at one year in all women and at three years in a subgroup of 1511 women. RESULTS: Randomization to estrogen plus progestin resulted in no significant effects on general health, vitality, mental health, depressive symptoms, or sexual satisfaction. The use of estrogen plus progestin was associated with a statistically significant but small and not clinically meaningful benefit in terms of sleep disturbance, physical functioning, and bodily pain after one year (the mean benefit in terms of sleep disturbance was 0.4 point on a 20-point scale, in terms of physical functioning 0.8 point on a 100-point scale, and in terms of pain 1.9 points on a 100-point scale). At three years, there were no significant benefits in terms of any quality-of-life outcomes. Among women 50 to 54 years of age with moderate-to-severe vasomotor symptoms at base line, estrogen and progestin improved vasomotor symptoms and resulted in a small benefit in terms of sleep disturbance but no benefit in terms of the other quality-of-life outcomes. CONCLUSIONS: In this trial in postmenopausal women, estrogen plus progestin did not have a clinically meaningful effect on health-related quality of life.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Although several studies comparing HT to a placebo have found that HT improves perceived sleep quality and self-reported sleeping problems more than a placebo [112-123]”
From Non-Pharmacological Treatment of Insomnia (2012) · cites this paper as [117]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
Radloff, L. S. (1977) · Applied Psychological Measurement · doi:10.1177/014662167700100306 · Cited by 53,267
(1992) · PubMed · Cited by 33,716
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033
Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889
MCHORNEY, C. A., JOHNE, W., & ANASTASIAE, R. (1993) · Medical Care · doi:10.1097/00005650-199303000-00006 · Cited by 6,681
Robins, L. N. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780290015001 · Cited by 5,219
The rand 36‐item health survey 1.0
Hays, R. D., Sherbourne, C. D., & Mazel, R. M. (1993) · Health Economics · doi:10.1002/hec.4730020305 · Cited by 2,971
(1987) · PubMed · Cited by 2,657
Design of the Women’s Health Initiative Clinical Trial and Observational Study
The Women’s Health Initiative Study Group (1998) · Controlled Clinical Trials · doi:10.1016/s0197-2456(97)00078-0 · Cited by 2,580
Research works printed but not linked: 2
- FDA approves new labels for estrogen and estrogen with progestin therapies for postmenopausal women following review of Women's Health Initiative data. Rockville, Md.: Food and Drug Administration, January 8, 2003.
- Teng EL, 1987, J Clin Psychiatry, 48, 314
Cited by
Sorted by citations
Items 401–500 of 685
Veerus, P., Fischer, K., Hovi, S., Hakama, M., Rahu, M., & Hemminki, E. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2005.12.037 · Cited by 9
Osteoporosis Classification Using Texture Features
Riaz, F., Nemati, R. J., Ajmal, H., Hassan, A., Edifor, E., & Nawaz, R. (2019) · Proceedings - IEEE Symposium on Computer-Based Medical Systems · doi:10.1109/cbms.2019.00119 · Cited by 9
Role of psychiatric comorbidity on cognitive function during and after the menopausal transition
Alexander, J. L., Sommer, B. R., Dennerstein, L., Grigorova, M., Neylan, T. C., Kotz, K. J., Richardson, G., & Rosenbaum, R. L. (2007) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.7.11s.s157 · Cited by 9
Ödmark, I. S., Bäckström, T. C., Jonsson, B., & Bixo, M. (2004) · Climacteric · doi:10.1080/13697130310001651526 · Cited by 9
Lamy, O., Krieg, M.-A., Burckhardt, P., & Wasserfallen, J. (2003) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.4.9.1479 · Cited by 9
Menopausal hormone therapy: Currently no evidence for cardiac protection
WENGER, N. K. (2005) · Pediatric Blood & Cancer · doi:10.1002/pbc.20348 · Cited by 9
The economic impact of symptomatic menopause among low-socioeconomic women in the United States
Keshishian, A. V., Wang, Y., Xie, L., & Başer, O. (2015) · Expert Review of Pharmacoeconomics & Outcomes Research · doi:10.1586/14737167.2015.1073589 · Cited by 8
Ovarian cancer prevention: Time for primetime?
Brawley, O. W. (2015) · Cancer · doi:10.1002/cncr.29347 · Cited by 8
Hormone replacement therapy in women with spinal cord injury – a survey with literature review
Khong, S., Savic, G. I., Gardner, B. P., & Ashworth, F. (2004) · Spinal Cord · doi:10.1038/sj.sc.3101694 · Cited by 8
Hormone Therapy Does Not Affect Depression Severity in Older Women
Goldstein, K. M., Harpole, L. H., Stechuchak, K. M., Coffman, C. J., Bosworth, H. B., Steffens, D. C., & Bastian, L. A. (2005) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200507000-00010 · Cited by 8
Reporting on post-menopausal hormone therapy: An analysis of gynaecologists' Web pages
Bucksch, J., Kolip, P., & Deitermann, B. (2004) · Medical Informatics and the Internet in Medicine · doi:10.1080/14639230400005958 · Cited by 8
shahdaeizadeh, S., organ, E., Edalatmanesh, M. A., & Moghadasi, M. (2014) · Pars of Jahrom University of Medical Sciences · doi:10.29252/jmj.12.4.8 · Cited by 8
Horiuchi, K., Yoshida, Y., & Okamoto, T. (2019) · Surgery Today · doi:10.1007/s00595-019-01830-9 · Cited by 8
Is hormone therapy still an option for the management of osteoporosis?
MacLennan, A. H., & Sturdee, D. W. (2003) · Climacteric · doi:10.1080/713605367 · Cited by 8
Naughton, M. J., Jones, A. S., & Shumaker, S. A. (2005) · Journal of Social Issues · doi:10.1111/j.0022-4537.2005.00399.x · Cited by 8
Hoover, R. N. (2008) · Epidemiology · doi:10.1097/ede.0b013e318188e21d · Cited by 8
Menopausal hormone therapy informed consent
Hendrix, S. L. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/s0002-9378(03)01097-4 · Cited by 8
Summary of Balancing Risks and Benefits
(2004) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000138791.21105.ce · Cited by 8
(2004) · Obstetrics and Gynecology · doi:10.1097/01.aog.0000138804.50006.7e · Cited by 9
Then and Now: What We Have Learned From the WHI
Lambrinoudaki, I. V., Armeni, E., Mili, N., & Anagnostis, P. G. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf638 · Cited by 8
Approach to Managing a Postmenopausal Patient
Santen, R. J., Heitjan, D. F., Gompel, A., Lumsden, M. A., Pinkerton, J. V., Davis, S. R., & Stuenkel, C. A. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa623 · Cited by 7
Risk of Depression during Menopause in Women from Poland, Belarus, Belgium, and Greece
Krajewska-Ferishah, K., Kułak-Bejda, A., Szyszko-Perłowska, A., Shpakou, A., Damme-Ostapowicz, K. V., & Chatzopulu, A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11123371 · Cited by 7
Quality of life assessment in a chemoprevention trial: Fenretinide and oral or transdermal HRT
Serrano, D., Mariani, L., Mora, S., Guerrieri‐Gonzaga, A., Cazzaniga, M., Daldoss, C., Ramazzotto, F., Feroce, I., DeCensi, A., & Bonanni, B. (2006) · Maturitas · doi:10.1016/j.maturitas.2006.01.005 · Cited by 7
Hormone replacement therapy: the risks and benefits of treatment
Hardie, C., Bain, C. J., & Walters, M. (2009) · The Journal of the Royal College of Physicians of Edinburgh · doi:10.4997/jrcpe.2009.408 · Cited by 7
Williams, B. R., & Cho, J. S. (2017) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2017.04.006 · Cited by 7
Christakis, M. K., Strobino, D. M., & Shen, W. (2019) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001387 · Cited by 7
Neurobiological Disturbances in Insomnia: Clinical Utility of Objective Measures of Sleep
Pejovic, S., & Vgontzas, A. N. (2010) · Medical psychiatry · doi:10.3109/9781420080803.007 · Cited by 7
“Up to general practice to pick up the pieces”—what pieces?—a response to WHI and MWS
Studd, J. W. W. (2003) · Maturitas · doi:10.1016/j.maturitas.2003.09.004 · Cited by 7
An energetics-based approach to understanding the menstrual cycle and menopause
Hall, R. L. (2004) · Human Nature · doi:10.1007/s12110-004-1005-9 · Cited by 7
Geller, M. L., & Chlebowski, R. T. (2003) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.08.003 · Cited by 7
Postmenopausal hormone therapy: the pros and cons
Rivera‐Woll, L., & Davis, S. R. (2004) · Internal Medicine Journal · doi:10.1111/j.1444-0903.2004.00555.x · Cited by 7
Assessing and managing breast cancer risk: clinical tools for advising patients.
Friedenson, B. (2004) · PubMed · Cited by 7
Clinical appraisal of the Women's Health Initiative
Speroff, L. (2005) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2005.00251.x · Cited by 7
WENGER, N. K. (2004) · Humana Press eBooks · doi:10.1007/978-1-59259-645-4_21 · Cited by 7
Depression and lipoprotein lipids in healthy, postmenopausal women
Brown, R. A., Giggey, P. P., Dennis, K. E., & Waldstein, S. R. (2004) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(03)00608-1 · Cited by 7
Targeting of Neuropharmaceuticals by Chemical Delivery Systems
Bodor, N. S., & Buchwald, P. (2006) · doi:10.1002/9783527611225.ch20 · Cited by 7
Sleep disordered breathing after menopause
Raphelson, J. R., Norby, B., Parra, G., DeYoung, P. N., Macaulay, K., Stuenkel, C. A., & Malhotra, A. (2026) · The Lancet Obstetrics Gynaecology & Women s Health · doi:10.1016/s3050-5038(25)00112-8 · Cited by 6
Haimov‐Kochman, R., Brzezinski, A., & Hochner‐Celnikier, D. (2011) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181fcd9d4 · Cited by 6
Sömjen, D., Katzburg, S., Baz, M., Stern, N., & Posner, G. H. (2004) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2004.03.022 · Cited by 6
Estrogen and progestogen therapy in postmenopausal women
(2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.07.1476 · Cited by 7
The effect of hormone replacement therapy on mood and everyday memory in younger mid-life women
Stephens, C. V., Pachana, N. A., & Bristow, V. (2006) · Psychology Health & Medicine · doi:10.1080/13548500600678180 · Cited by 6
Coding and Evaluating Facilitator Posts for an Online Cancer Survivor Workshop
Gits, A., Ritter, P. L., Plant, K., & Lorig, K. R. (2013) · Journal of Psychosocial Oncology · doi:10.1080/07347332.2012.761321 · Cited by 6
Ouzounian, S., & Christin‐Maître, S. (2005) · PubMed · Cited by 6
Comparison of effects of two different hormone therapies on mood in symptomatic postmenopausal women
Karşıdağ, Ç., Karşıdağ, A. Y. K., Büyükbayrak, E. E., Kars, B., Pirimoğlu, M., Ünal, O., & Turan, C. (2012) · Nöro Psikiyatri Arşivi · Cited by 6
Estrogen and progestogen therapy in postmenopausal women
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2003.10.002 · Cited by 6
Time to review all the evidence for hormone replacement therapy
Crawford, F., & Langhorne, P. (2005) · BMJ · doi:10.1136/bmj.330.7487.345 · Cited by 6
Where are we with postmenopausal hormone therapy in 2005?
Lam, P. M., Chung, T. K. H., & Haines, C. J. (2005) · Gynecological Endocrinology · doi:10.1080/09513590500279733 · Cited by 6
Using a Drug Before the Risks and Benefits Are Known From a Phase 3 Clinical Trial
Miller, J. W. (2006) · Archives of Ophthalmology · doi:10.1001/archopht.124.7.1029 · Cited by 6
Rozenbaum, H. (2007) · EMC - Gynécologie · doi:10.1016/s0246-1064(07)43139-5 · Cited by 6
Londero, A. P., Gallina, V., Cremonini, F., Xholli, A., & Cagnacci, A. (2024) · Maturitas · doi:10.1016/j.maturitas.2024.108105 · Cited by 6
Glynne, S., Kamal, A., McColl, L., Newson, L. R., Reisel, D., Mu, E., Hendriks, O., Saini, P., Gurvich, C., & Kulkarni, J. (2025) · The British Journal of Psychiatry · doi:10.1192/bjp.2025.101 · Cited by 5
Menopausal Hormone Therapy: What We Know Now
Roush, K. M. (2011) · AJN American Journal of Nursing · doi:10.1097/01.naj.0000398539.52283.55 · Cited by 5
Medical Decisions, Estrogen and Aging
Schulkin, J. A. (2007) · Springer eBooks · doi:10.1007/978-1-4020-6686-3 · Cited by 5
Monophasic Estrogen-Progestogen Therapy and Sexuality in Postmenopausal Women
da Fonseca, Â. M., Bagnoli, V. R., Penteado, S. R. L., o, J. S. P., Cavalcanti, A. L., & Pinotti, J. A. (2007) · Clinical Drug Investigation · doi:10.2165/00044011-200727020-00006 · Cited by 5
Turbulent Times for Hormone Replacement Therapy: Is There a Way Out?
Verhaeghe, J. (2003) · Gynecologic and Obstetric Investigation · doi:10.1159/000072483 · Cited by 5
Tratamiento hormonal sustitutivo y enfermedades cardiovasculares
WENGER, N. K. (2006) · Revista Española de Cardiología · doi:10.1157/13093983 · Cited by 5
Laser acupuncture does not improve menopausal symptoms
O’Brien, K., Varigos, E., Black, C. V. S., & Komesaroff, P. A. (2010) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e3181c72b9d · Cited by 5
Hormone Replacement Therapy in Endometrial Cancer Survivors
McDonnell, B. A., & Twiggs, L. B. (2006) · Journal of Lower Genital Tract Disease · doi:10.1097/01.lgt.0000210128.93392.65 · Cited by 5
Genazzani, A. R., Gambacciani, M., Simoncini, T., Anniverno, R., Becorpi, A. M., Biglia, N., Brandi, M. L., Guaschino, S., Lello, S., Massobrio, M., et al. (2007) · Gynecological Endocrinology · doi:10.1080/09513590701577869 · Cited by 5
Gold, D. T., & Silverman, S. L. (2007) · Current Osteoporosis Reports · doi:10.1007/bf02938616 · Cited by 5
Predictors of quality of life in peri- and postmenopausal Polish women living in Lublin Voivodeship
Żołnierczuk-Kieliszek, D., Kulik, T. B., & Pacian, A. B. (2011) · Climacteric · doi:10.3109/13697137.2011.584001 · Cited by 5
Health Related Quality of Life Outcome Measures
Downey, P. A. (2005) · Journal of Womenʼs Health Physical Therapy · doi:10.1097/01274882-200529020-00003 · Cited by 5
Maki, P. M. (2007) · Elsevier eBooks · doi:10.1016/b978-012369443-0/50027-2 · Cited by 5
World Health Organization ( WHO ): Global Health Situation
Hapsara, H. R. (2008) · Wiley Encyclopedia of Clinical Trials · doi:10.1002/9780471462422.eoct992 · Cited by 5
Update in General Internal Medicine
Sheffield, J. V. L., & Larson, E. B. (2003) · Annals of Internal Medicine · doi:10.7326/0003-4819-139-4-200308190-00011 · Cited by 5
KHAN, M. G. (2006) · Elsevier eBooks · doi:10.1016/b978-012406061-6/50093-x · Cited by 5
Langhe, R., Kelly, T., Ibrahim, R., Al‐Janabi, R., Mohammed, G., & Mousa, N. A. (2025) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.70728 · Cited by 4
Breast Cancer Basics: Understanding the Disease and Its Challenges
Mutthuraj, D., Brunda, M., Sajana, M., & Basalingappa, K. M. (2026) · Springer eBooks · doi:10.1007/978-981-95-3682-5_2 · Cited by 4
Long-term hormone therapy for perimenopausal and postmenopausal women
Rodriguez, M. B., Yong, L. N., Mirkov, S., Bekos, C., Lethaby, A. E., & Farquhar, C. M. (2026) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004143.pub7 · Cited by 5
Review- non-hormonal therapies for the treatment of menopausal symptoms
Elhelw, B. (2006) · Bioline International (Bioline International) · Cited by 3
An Evidence-Based Future for Menopausal Hormone Therapy
Banks, E. (2015) · Women s Health · doi:10.2217/whe.15.37 · Cited by 4
Neurobiological Disturbances in Insomnia: Clinical Utility of Objective Measures of Sleep
Pejovic, S., & Vgontzas, A. N. (2016) · doi:10.3109/9781420080803-9 · Cited by 4
He, Q., Ren, Y., Wang, Y., Zhang, F., & Zhang, S. (2020) · Medicine · doi:10.1097/md.0000000000019366 · Cited by 4
Chapurlat, R. D., & Genant, H. K. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00069-x · Cited by 4
Evaluation of the sexual function and quality of life in raloxifene treated postmenopausal women
Bırı, A., Korucuoğlu, Ü., ILHAN, M. N., Ciftci, B., Bozkurt, N., & Güner, H. (2008) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-008-0752-y · Cited by 4
Mitchell, J. L., Walsh, J. M. E., Wang-Cheng, R. M., & Hardman, J. (2003) · Primary Care Clinics in Office Practice · doi:10.1016/s0095-4543(03)00093-9 · Cited by 4
Hudson, T. (2004) · Alternative and Complementary Therapies · doi:10.1089/107628004772830401 · Cited by 4
Hormone Therapy, Dilemmas, Medical Decisions
Schulkin, J. A. (2008) · The Journal of Law Medicine & Ethics · doi:10.1111/j.1748-720x.2008.00239.x · Cited by 4
Phytoestrogen Extraction for Relaxation of Female Menopause Symptoms from Natural Products
Lee, S. B., Park, S. Y., Jeon, G. S., & Hong, I. K. (2016) · Applied Chemistry for Engineering · doi:10.14478/ace.2016.1023 · Cited by 4
Sex Differences in Neuroanatomy and Neurophysiology
Neigh, G. N., & Merrill, L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802388-4.00003-3 · Cited by 4
Lamberts, S. W. J. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0324-5.00027-4 · Cited by 4
A review of menopausal hormone therapy: recalibrating the balance of benefit and risk
Rajan, S., & Kreatsoulas, C. (2019) · Polskie Archiwum Medycyny Wewnętrznej · doi:10.20452/pamw.4412 · Cited by 4
Reassessing Benefits and Risks of Hormone Therapy
Gass, M. L. S., Bassuk, S. S., & Manson, J. E. (2008) · American Journal of Lifestyle Medicine · doi:10.1177/1559827608323216 · Cited by 4
Hormontherapie um die Menopause
Seifert‐Klauss, V., & Schumm‐Draeger, P. (2003) · Der Internist · doi:10.1007/s00108-003-1080-8 · Cited by 4
Moe, K. E. (2005) · Elsevier eBooks · doi:10.1016/b0-72-160797-7/50117-8 · Cited by 4
Estrogen and progestogen therapy in postmenopausal women
(2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.05.006 · Cited by 4
Cardiovascular Health in Women—Across the Lifespan
Chandrasekhar, J., Yao, J. V., Gong, S., Wijayarathne, P. M., Watts, M., & Mukherjee, S. (2025) · Clinical Endocrinology · doi:10.1111/cen.70027 · Cited by 5
Foschi, M., Groccia, G., Rusce, M. L., Medaglia, C., Aio, C., Sponzilli, A., Setti, V., Battipaglia, C., & Genazzani, A. D. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14207328 · Cited by 3
Effects of Koryo Hand Therapy on Menopausal Symptoms and FSH, LH, and Estradiol in Climacteric Women
Song, Y. A., & Shin, H. S. (2009) · Journal of Korean Academy of Nursing · doi:10.4040/jkan.2009.39.6.868 · Cited by 3
Sleep and Sleep Disorders in Women
Driver, H. S., & Sloan, E. P. (2017) · Springer eBooks · doi:10.1007/978-1-4939-6578-6_53 · Cited by 3
Meta-analysis, Medical Reversal, and Settled Science
Nunnally, M., & Tung, A. (2018) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000002661 · Cited by 3
Menopausal Hormone Therapy: A Safety Perspective
Banks, E. (2014) · Springer eBooks · doi:10.1007/978-3-319-12406-3_11 · Cited by 3
Menopause, cessation of menses, vs. “menopause”, a primary brain disorder?
Jaffe, S. L. (2013) · Advances in Bioscience and Biotechnology · doi:10.4236/abb.2013.46a003 · Cited by 3
Climacteric Symptoms: Importance and Management
Birkhaeuser, M. H. (2018) · ISGE series · doi:10.1007/978-3-319-63540-8_4 · Cited by 5
Bone Density and Imaging of Osteoporosis
Chapurlat, R. D., Delmas, P. D., & Genant, H. K. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00068-x · Cited by 3
Cancer Survivors: A Physician’s Perspective
Ganz, P. A. (2007) · Springer eBooks · doi:10.1007/978-0-387-68265-5_1 · Cited by 3
Klinik der Perimenopause, der Postmenopause und des Seniums
Ortmann, O., & Hadji, P. (2009) · Springer eBooks · doi:10.1007/978-3-540-89760-6_20 · Cited by 3
¿Se debe tratar la menopausia?
Bailón, E. T. L. (2004) · Atención Primaria · doi:10.1016/s0212-6567(04)79395-6 · Cited by 3
Nachtigall, L. E. (2009) · Nature Reviews Endocrinology · doi:10.1038/ncpendmet1079 · Cited by 3
Hormones and Quality of Life after Surgical Menopause
Utian, W. H. (2006) · Journal of Women s Health · doi:10.1089/jwh.2006.15.975 · Cited by 3
Metadata
- Authors
- Hays, J., Ockene, J. K., Brunner, R. L., Kotchen, J. M., Manson, J. E., Patterson, R. E., Aragaki, A. K., Shumaker, S. A., Brzyski, R. G., LaCroix, A. Z., Granek, I. A., & Valanis, B. G.
- Affiliations
- University of Massachusetts Chan Medical School (US)
- University of Nevada, Reno (US)
- Medical College of Wisconsin (US)
- Brigham and Women's Hospital (US)
- Fred Hutch Cancer Center (US)
- Wake Forest University Health Sciences (US)
- The University of Texas at San Antonio Health Science Center (US)
- State University of New York (US)
- Kaiser Permanente Center for Health Research (US)
- ORCID
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2003-05-08
- Volume
- 348
- Issue
- 19
- Pages
- 1839-1854
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2110502449
- Cited by
- 686
- References
- 36
- Citations by year
- 2026: 6 · 2025: 14 · 2024: 2 · 2023: 4 · 2022: 7 · 2021: 9 · 2020: 6 · 2019: 11 · 2018: 12 · 2017: 9 · 2016: 17 · 2015: 15 · 2014: 18 · 2013: 23 · 2012: 25
- FWCI
- 66.22
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- eScholarship@UMassChan (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Keywords
- estrogen plus progestin, hormone therapy, health-related quality of life, postmenopausal women, conjugated equine estrogens, medroxyprogesterone acetate, vasomotor symptoms, sleep disorders, physical function, bodily pain, depressive symptoms, sexual satisfaction, Women's Health Initiative
- MeSH terms
- Aged, Cognition, Depression, Estrogens, Female, Health Status, Humans, Mental Health, Middle Aged, Progestins, Quality of Life, Sexual Behavior, Sleep Wake Disorders, Estrogen Replacement Therapy, Linear Models, Hot Flashes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
