GAD treatment and insulin secretion in recent-onset type 1 diabetes

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Items 301–400 of 520

1. Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets
   Anna Moser, Hsiang‐Ting Hsu, Peter Van Endert · 2010 · F1000 Biology Reports
2. The need and benefit of immune monitoring to define patient and disease heterogeneity, mechanisms of therapeutic action and efficacy of intervention therapy for precision medicine in type 1 diabetes
   Bart O. Roep · 2023 · Frontiers in Immunology
3. GABA and Combined GABA with GAD65-Alum Treatment Alters Th1 Cytokine Responses of PBMCs from Children with Recent-Onset Type 1 Diabetes
   Katie E. Heath, Joseph M. Feduska, Jared P. Taylor, Julie A. Houp, Davide Botta, Frances E. Lund, Gail J. Mick, Gerald G. McGwin, Kenneth L. McCormick, Hubert Ming Tse · 2023 · Biomedicines
4. Is it time to challenge the established theories surrounding type 1 diabetes?
   Johnny Ludvigsson · 2014 · Acta Paediatrica
5. Targeting Lymphoid Tissues to Promote Immune Tolerance
   Xiao Yan Chen, Guang Sheng Du, Xun Sun · 2021 · Advanced Therapeutics
6. Phase III, randomised, double-blind, placebo-controlled, multicentre trial to evaluate the efficacy and safety of rhGAD65 to preserve endogenous beta cell function in adolescents and adults with recently diagnosed type 1 diabetes, carrying the genetic HLA DR3-DQ2 haplotype: the DIAGNODE-3 study protocol
   Johnny Ludvigsson, Linnea Eriksson, Christoph Nowak, Pedro Filipe Teixeira, Martina Widman, Anton Lindqvist, Rosaura Casas, Marcus Lind, Ulf Hannelius · 2022 · BMJ Open
7. Antihyperglycemic and antioxidative effect of hydro - methanolic (2:3) extract of the seed of Swietenia mahagoni (L.) Jacq. in streptozotocin-induced diabetic male albino rat: An approach through pancreas
   Tushar Kanti Bera, Kausik Chatterjee, Kishalay Jana, Kazi Monjur Ali, Debasis De, Soumyajit Maiti, Debidas Ghosh · 2012 · Genomic Medicine Biomarkers and Health Sciences
8. Regulatory Function of a Novel Population of Mouse Autoantigen-Specific Foxp3− Regulatory T Cells Depends on IFN-γ, NO, and Contact with Target Cells
   Cyndi Chen, Chih‐Pin Liu · 2009 · PLoS ONE
9. Recent advances in adrenal autoimmunity
   Alberto Falorni, Annalisa Brozzetti, Filippo Calcinaro, Stefania Marzotti, Fausto Santeusanio · 2009 · Expert Review of Endocrinology & Metabolism
10. Have we pushed the needle for treatment of Type 1 diabetes?
    Nida Naushad, Ana Luisa Perdigoto, Jinxiu Rui, Kevan C. Herold · 2017 · Current Opinion in Immunology
11. Association between treatment effect on C‐peptide preservation and HbA1c in meta‐analysis of glutamic acid decarboxylase (GAD)‐alum immunotherapy in recent‐onset type 1 diabetes
    Christoph Nowak, Ulf Hannelius, Johnny Ludvigsson · 2022 · Diabetes Obesity and Metabolism
12. Immunotherapy Trials for Type 1 Diabetes: The Contribution of George Eisenbarth
    Jay S. Skyler, Alberto Pugliese · 2013 · Diabetes Technology & Therapeutics
13. Low C-peptide levels and decreased expression of TNF and CD45 in children with high risk of type 1 diabetes
    Linda Åkerman, Johnny Ludvigsson, Rosaura Casas · 2013 · Clinical Immunology
14. Glucose intolerance and diabetes following antigen-specific insulitis in diabetes-susceptible “humanized” transgenic mice
    Raya B. Elagin, Juan Carlos Jaume · 2010 · Biochemical and Biophysical Research Communications
15. GAD-alum (Diamyd) – a new concept for preservation of residual insulin secretion
    Johnny Ludvigsson · 2010 · Expert Opinion on Biological Therapy
16. A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes
    Jeniffer D Loaiza Naranjo, Anne‐Sophie Bergot, Irina Buckle, Emma E. Hamilton‐Williams · 2020 · Current Diabetes Reports
17. Strategies and delivery systems for cell-based therapy in autoimmunity
    Matteo Puccetti, Claudio Costantini, Aurélie Schoubben, Stefano Giovagnoli, Maurizio Ricci · 2024 · Frontiers in Drug Delivery
18. Immunotherapy-Based Strategies for Treatment of Type 1 Diabetes
    Laura M. Jacobsen, Desmond Schatz · 2024 · Hormone Research in Paediatrics
19. Antigen-based immunotherapies do not prevent progression of recent-onset autoimmune diabetes: a systematic review and meta-analysis
    Chrysoula Rizava, Eleni Bekiari, Aris Liakos, Maria Sarigianni, Maria Rika, Anna‐Bettina Haidich, Assimina Galli‐Τsinopoulou, Απόστολος Τσάπας · 2016 · Endocrine
20. Polyvalent therapeutic vaccine for type 2 diabetes mellitus: Immunoinformatics approach to study co-stimulation of cytokines and GLUT1 receptors
    Syed Aun Muhammad, Hiba Ashfaq, Sidra Zafar, Fahad Munir, Muhammad Babar Jamshed, Jake Y. Chen, Qiyu Zhang · 2020 · BMC Molecular and Cell Biology
21. Clinical Potential of Antigen-Specific Therapies in Type 1 Diabetes
    Ken T. Coppieters, Birgit Sehested Hansen, Matthias G. von Herrath · 2012 · The Review of Diabetic Studies
22. The Potential Utility of Bone Marrow or Umbilical Cord Blood Transplantation For the Treatment of Type I Diabetes Mellitus
    Mohamed Mabed · 2010 · Transplantation and Cellular Therapy
23. IL-13Rα1 Expression on β-Cell–Specific T Cells in NOD Mice
    Sarah Rasché, Michele Phillips, Marcia F. McInerney, Eli E. Sercarz, Anthony Quinn · 2011 · Diabetes
24. Recognition of heat shock protein 60 epitopes in children with type 1 diabetes
    A. A. Verrijn Stuart, Wilco de Jager, Mark R. Klein, Gijs Teklenburg, Roos Nuboer, J. J. Gera Hoorweg-Nijman, Monique De Vroede, Ineke de Kruijff, M. Fick, Eelco J. Schroor et al. · 2012 · Diabetes/Metabolism Research and Reviews
25. Mechanisms and early patterns of dyslipidemia in pediatric type 1 and type 2 diabetes
    Benjamin Udoka Nwosu, Tony R. Villalobos-Ortiz, Gabrielle Jasmin, Sadichchha Parajuli, Emily Zitek‐Morrison, BRUCE A. BARTON · 2020 · Journal of Pediatric Endocrinology and Metabolism
26. Administration of a determinant of preproinsulin can induce regulatory T cells and suppress anti-islet autoimmunity in NOD mice
    Takashi Arai, Hiroaki Moriyama, Mami Shimizu, Hirotomo Sasaki, Minoru Kishi, Yasuyo Okumachi, Hisafumi Yasuda, Kenta Hara, Koichi Yokono, Masao Nagata · 2010 · Clinical Immunology
27. New prospects for immunotherapy at diagnosis of type 1 diabetes
    Paolo Pozzilli, Richard David Leslie · 2009 · Diabetes/Metabolism Research and Reviews
28. New Perspectives in Studying Type 1 Diabetes Susceptibility Biomarkers
    Y.B. Park, Kyung Soo Ko, Byoung Doo Rhee · 2025 · International Journal of Molecular Sciences
29. The Effect of Diabetes-Associated Autoantigens on Cell Processes in Human PBMCs and Their Relevance to Autoimmune Diabetes Development
    Jana Včeláková, Radek Blatný, Zbyněk Halbhuber, Michal Kolář, Aleš Neuwirth, Lenka Petruželková, Tereza Ulmannová, Stanislava Koloušková, Zdenĕk Šumnı́k, Pavlína Piťhová et al. · 2013 · Journal of Diabetes Research
30. Latent Autoimmune Diabetes in Adults: Background, Safety and Feasibility of an Ongoing Pilot Study With Intra-Lymphatic Injections of GAD-Alum and Oral Vitamin D
    Anneli Björklund, Ingrid Kathrin Hals, Valdemar Grill, Johnny Ludvigsson · 2022 · Frontiers in Endocrinology
31. Re-Enlightenment of Fulminant Type 1 Diabetes under the COVID-19 Pandemic
    Hiroyuki Sano, Akihisa Imagawa · 2022 · Biology
32. HLA‐DR3 mediated CD4 T cell response against GAD65 in type 1 diabetes patients
    Neihenuo Chuzho, Neetu Mishra, Nikhil Tandon, Uma Kanga, Gunja Mishra, Akanksha Sharma, Narinder Kumar Mehra, Neeraj Kumar · 2023 · Journal of Diabetes
33. Immune biomarkers in immunotherapeutic trials for type 1 diabetes: Cui prodest?
    Slobodan Čulina, Roberto Mallone · 2012 · Diabetes & Metabolism
34. β-cell preservation and regeneration for diabetes treatment: where are we now?
    Michael Karadimos, Archana Kapoor, Ilham El Khattabi, Arun Sharma · 2012 · Diabetes Management
35. New era of therapy for endocrine autoimmune disorders
    Bergithe Eikeland Oftedal, Anette S. B. Wolff · 2020 · Scandinavian Journal of Immunology
36. Clinical Characteristics and Laboratory Findings of Children who were Newly Diagnosed with Diabetes Mellitus (From 2001 to 2008)
    Eun Hui Hong, Junseok Park, Hwan Seok Lee, Min Hyun Cho, Cheol Woo Ko · 2009 · Journal of Korean Society of Pediatric Endocrinology
37. Gastrointestinal Tract and Endocrine System
    Nonsikelelo Mpofu, Michelle A. Klose, Elmar Jäckel, Michael Peter Manns, Oliver P. Bachmann · 2013 · Springer eBooks
38. Type 1 Diabetes in Adults
    Serge A Jabbour · 2010 · The Medicine Forum
39. It's Time to Consider Changing the Rules
    Mark A. Atkinson · 2011 · Diabetes
40. A 1‐year pilot study of intralymphatic injections of GAD‐alum in individuals with latent autoimmune diabetes in adults (LADA) with signs of high immunity: No safety concerns and resemblance to juvenile type 1 diabetes
    Ingrid Kathrin Hals, Chandima N. D. Balasuriya, Rosaura Casas, Johnny Ludvigsson, Anneli Björklund, Valdemar Grill · 2023 · Diabetes Obesity and Metabolism
41. Immunomodulatory interventions in type 1 diabetes: a systematic review and meta-analysis revealing paradoxical dissociation between beta-cell preservation and glycemic control
    Shankar Kumar Biswas, Bhavya Dhir, Susmitha Talasila, SPURTHY SRI NAMALA, Ankush Kimmatkar, Neeharika Bhamidi, Sudharshan Raajkumar Ezhil, Ummul Barka Safa, Reza Imankhah, Vamsi Priya Sribhashyam et al. · 2025 · BMC Endocrine Disorders
42. Reversal of diabetes by an oral Salmonella-based vaccine in acute and progressive diabetes in NOD mice
    Jacob Cobb, Jeffrey Rawson, Nelson Gonzalez, Chris Orr, FOUAD R. KANDEEL, Mohamed Ibrahim Husseiny · 2024 · PLoS ONE
43. Type 1 diabetes mellitus—a door opening to a real therapy?
    Lucienne Chatenoud · 2011 · Nature Reviews Endocrinology
44. Autoantibody Positivity and Clinical Characteristics of Diabetes Mellitus in Childhood
    Jiyun Park, Jong‐seok Oh, Jeesuk Yu · 2011 · Journal of Korean Society of Pediatric Endocrinology
45. Treatment options for paediatric diabetes
    Alberto Verrotti, Rosa Maria Chiuri, Annalisa Blasetti, Angelika Mohn, Francesco Chiarelli · 2010 · Expert Opinion on Pharmacotherapy
46. Can we vaccinate against Type 1 diabetes?
    Mark Peakman · 2012 · F1000 Biology Reports
47. Recent Advances in Management of Diabetes Mellitus
    Mohammad Ashraf Ganie, Suman Kumar Kotwal · 2012
48. Immune Intervention in Children with Type 1 Diabetes
    for The Linköping Diabetes Immune Intervention study group, Johnny Ludvigsson · 2010 · Current Diabetes Reports
49. GAD autoantibody epitope pattern after GAD-alum treatment in children and adolescents with type 1 diabetes
    Camilla Skoglund, Mikael Chéramy, Rosaura Casas, Johnny Ludvigsson, Christiane S. Hampe · 2011 · Pediatric Diabetes
50. The Juvenile Diabetes Research Foundation at Forty: Updates of Research in Type 1 Diabetes
    Concepcion R. Nierras, Mark A. Atkinson, Robert A. Goldstein · 2010 · Diabetes
51. From islet transplantation to beta-cell regeneration: an update on beta-cell-based therapeutic approaches in type 1 diabetes
    Asef Azad, Hasan Altunbaş, Ayşe Esra Manguoğlu · 2024 · Expert Review of Endocrinology & Metabolism
52. Therapeutic Uses of Stem Cells in Endocrinology- Review Article
    Ensieh Nasli‐Esfahani, Ardeshir Ghavamzadeh, Bagher A. Larijani · 2014 · DOAJ (DOAJ: Directory of Open Access Journals)
53. Type 1 Diabetes Therapy Beyond T Cell Targeting: Monocytes, B Cells, and Innate Lymphocytes
    Florence Susan Wong, Wen Li · 2012 · The Review of Diabetic Studies
54. Inverse vaccination with islet autoantigens to halt progression of autoimmune diabetes
    Simon A. Hinke · 2011 · Drug Development Research
55. Immunotherapy on Trial for New-Onset Type 1 Diabetes
    Denise Louise Faustman · 2008 · New England Journal of Medicine
56. More on Intralymphatic Injection of Autoantigen in Type 1 Diabetes
    Johnny Ludvigsson, Beatriz Tavira, Rosaura Casas · 2017 · New England Journal of Medicine
57. Leveraging circulating microRNAs for personalized disease-modifying therapies in type 1 diabetes
    Giuseppina Emanuela Grieco, Francesco Dotta, Guido Sebastiani · 2025 · Personalized Medicine
58. Regulatory T cell-based therapies for type 1 diabetes: a narrative review
    Tsvetelina Veselinova Velikova, Georgi Vasilev, Diya Linkwinstar, Elina Siliogka, Maria Kokudeva, Dimitrina Miteva, Georgi Vasilev, Milena Gulinac, Kiril Atliev, Russka Shumnalieva · 2025 · Metabolism and Target Organ Damage
59. Clinical trials of promising apoptosis modulating drugs
    Nikita Sharma, R. Mankamna Kumari, Geeta Arya, Nidhi Gupta, Ramesh Chandra, Surendra Nimesh · 2020 · Elsevier eBooks
60. Dead or Alive?
    Carla J. Greenbaum · 2012 · Diabetes Care
61. Glutamic acid decarboxylase immunotherapy for type 1 diabetes
    Johnny Ludvigsson · 2022 · Current Opinion in Endocrinology Diabetes and Obesity
62. Type 1 diabetes: key drug targets and how they could influence future therapeutics
    Yoon Kook Kim, Kashif M. Munir, Stephen N. Davis · 2023 · Expert Opinion on Therapeutic Targets
63. An update on the pharmacotherapy options for pediatric diabetes
    Maria Loredana Marcovecchio, Francesco Chiarelli · 2014 · Expert Opinion on Biological Therapy
64. Update on Global Intervention Studies in Type 1 Diabetes
    Jane L. Chiang, Michael J. Haller, Desmond Schatz · 2012 · Endocrinology and Metabolism Clinics of North America
65. Immunoendocrinopathy syndromes
    WA Scherbaum, M. Schott · 2011
66. Ketoacidosis at diagnosis of type 1 diabetes in children under 15 years of age
    Anne Hekkala · 2016
67. Redosing with Intralymphatic GAD-Alum in the Treatment of Type 1 Diabetes: The DIAGNODE-B Pilot Trial
    Rosaura Casas, Andrea Tompa, Karin Åkesson, Pedro Filipe Teixeira, Anton Lindqvist, Johnny Ludvigsson · 2025 · International Journal of Molecular Sciences
68. Exploring the progress and trends of immunotherapy for type 1 diabetes: A comprehensive bibliometric analysis spanning nearly two decades
    Yixin Jiang, Zhou Xu, Yuting Wu, Xinglei Li, Jitao Ling, Yixuan Chen, Zicheng Zhu, Pingping Yang, Xiao Liu, Deju Zhang et al. · 2025 · Obesity Reviews
69. Novel delivery mechanisms for antigen-specific immunotherapy
    Tobias Neef, Stephen D. Miller · 2021 · Current Opinion in Endocrinology Diabetes and Obesity
70. Preventing type 1 diabetes in late-stage pre-diabetic NOD mice with insulin: A central role for alum as adjuvant
    P. Martens, Darcy Ellis, Ylke Bruggeman, Marijke Viaene, J. Laureys, L. Teyton, C. Mathieu, C. Gysemans · 2022 · Frontiers in Endocrinology
71. Safely targeting autoimmunity in type 1 diabetes: the MonoPepT1De trial
    YF Liu, Mark Peakman, Colin Mark Dayan · 2013 · Practical Diabetes
72. Update on Treatment of Type 1 Diabetes in Childhood
    Johnny Ludvigsson · 2013 · Current Pediatrics Reports
73. Struggles With Clinical Translation of Immune Intervention Trials
    Jay S. Skyler · 2014 · Diabetes Care
74. Vaccines for metabolic diseases: current perspectives
    Mariana Pereira Monteiro, Tiago Morais, Sara Andrade, Sofia Silva Pereira · 2014 · Vaccine Development and Therapy
75. Type 1 diabetes research: Newer approaches and exciting developments
    CB Sanjeevi · 2009 · International Journal of Diabetes in Developing Countries
76. Stimulating IL-13 Receptors on T cells: A New Pathway for Tolerance Induction in Diabetes?
    Florence Susan Wong · 2011 · Diabetes
77. Type 1 diabetes mellitus: immune intervention
    Jay S. Skyler · 2012 · International Journal of Clinical Practice
78. Regulatory T Cells in Autoimmune Diabetes
    Vitalijs Ovcinnikovs, Lucy S. K. Walker · 2015 · Progress in molecular biology and translational science
79. M2-like macrophages and tumor-associated macrophages: overlapping and distinguishing properties en route to a safe therapeutic potential
    Ofer Guttman, Eli C. Lewis · 2016 · Integrative Cancer Science and Therapeutics
80. Prevention of Type 1 Diabetes
    Jay S. Skyler · 2018 · Endocrinology
81. A study on the role of genes of innate immunity in type 1 diabetes
    Saikiran K. Sedimbi · 2010 · Figshare
82. Glutamic Acid Decarboxylase Therapy for Recent-Onset Type 1 Diabetes: Are We at the End or the Beginning of Finding a Cure?
    G. Alexander Fleming, David Charles Klonoff · 2009 · Journal of Diabetes Science and Technology
83. Weight gain in children : possible relation to the development of diabetes
    Karina Huus · 2009 · DiVA (Linkoping University)
84. Estrategias de terapia celular para el tratamiento de la diabetes tipo 1: dónde estamos y qué podemos esperar
    Miguel Barajas · 2011 · Avances en Diabetología
85. Recurrence of type 1 diabetes following simultaneous pancreas-kidney transplantation
    George William Burke, Gaetano Ciancio, Mahmoud Morsi, Jose Figueiro, Linda Chen, Francesco Vendrame, Alberto Pugliese · 2019 · Elsevier eBooks
86. Prevention of β-Cell Destruction in Autoimmune Diabetes: Current Approaches and Future Prospects
    Saikiran K. Sedimbi, Carani B. Sanjeevi · 2010 · Advances in experimental medicine and biology
87. L’augmentation d’incidence du diabète de type 1 : la réalité du diabète de l’enfant ?
    Claire Lévy‐Marchal · 2010 · Médecine des Maladies Métaboliques
88. Less Is More: The Detrimental Consequences of Immunosuppressive Therapy in the Treatment of Type-1 Diabetes
    Nadir Askenasy · 2015 · International Reviews of Immunology
89. Ingested Type I Interferon—State of the Art as Treatment for Autoimmunity Part 2
    Staley A. Brod · 2010 · Pharmaceuticals
90. On the Occurrence of the Diabetes-Associated Antigen GAD 65 in Human Sera
    Gernot P. Tilz, Marco Wiltgen, MH Borkenstein · 2010 · International Archives of Allergy and Immunology
91. Therapeutics in pediatric diabetes: Insulin and non-insulin approaches
    Jongoh Kim, Se Min Kim, Ha Cam Thuy Nguyen, MARIA JOSE REDONDO · 2011 · Pharmacological Research
92. Understanding the Immunology of Type 1 Diabetes— An Overview of Current Knowledge and Perspectives for the Future
    Anil Piya, Aaron W. Michels, Pediatric Endocrinology Fellow · 2012 · US Endocrinology
93. Diabetes mellitus Typ 1
    Michael Hummel, Peter Achenbach · 2015 · Der Internist
94. LADA
    Simona Zampetti, Raffaella Buzzetti · 2018 · Endocrinology
95. Type 1 Diabetes
    Mark A. Atkinson, Jay S. Skyler · 2011 · Springer eBooks
96. Autoimmune Endocrine Disorders
    Jennifer M. Barker · 2018 · Springer eBooks
97. Immunotherapy of Type-1 Diabetes: Immunoprevention and Immunoreversal
    Frank Waldron-Lynch, Kevan C. Herold · 2010 · Humana Press eBooks
98. Adiponectin and immune tolerance in type 1 diabetes
    Terence Pang · 2011 · University of Birmingham Institutional Research Archive (University of Birmingham)
99. Prevention of Type 1 Diabetes
    Jay S. Skyler · 2010 · Wiley eBooks
100. Immunotherapy for Type 1 Diabetes: Mechanistic Insights and Impact of Delivery Systems
     Nishi Agrawal, Ganesh Kumar, Sree Prakash Pandey, Shweta Yadav, Manoj Kumar, M. S. Sudheesh, Ravi Shankar Pandey · 2024 · Current Pharmaceutical Design