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The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Outcomes of Treatment for Hepatitis C Virus Infection by Primary Care Providers

Open access
Arora, Sanjeev, Thornton, Karla, Murata, Glen, Deming, Paulina, Kalishman, Summers, Dion, Denise, Parish, Brooke, Burke, Thomas, Pak, Wesley, Dunkelberg, Jeffrey, Kistin, Martin, Brown, John, Jenkusky, Steven, Komaromy, Miriam, Qualls, Clifford·2011·New England Journal of Medicine

Abstract

BACKGROUND: The Extension for Community Healthcare Outcomes (ECHO) model was developed to improve access to care for underserved populations with complex health problems such as hepatitis C virus (HCV) infection. With the use of video-conferencing technology, the ECHO program trains primary care providers to treat complex diseases. METHODS: We conducted a prospective cohort study comparing treatment for HCV infection at the University of New Mexico (UNM) HCV clinic with treatment by primary care clinicians at 21 ECHO sites in rural areas and prisons in New Mexico. A total of 407 patients with chronic HCV infection who had received no previous treatment for the infection were enrolled. The primary end point was a sustained virologic response. RESULTS: A total of 57.5% of the patients treated at the UNM HCV clinic (84 of 146 patients) and 58.2% of those treated at ECHO sites (152 of 261 patients) had a sustained viral response (difference in rates between sites, 0.7 percentage points; 95% confidence interval, -9.2 to 10.7; P=0.89). Among patients with HCV genotype 1 infection, the rate of sustained viral response was 45.8% (38 of 83 patients) at the UNM HCV clinic and 49.7% (73 of 147 patients) at ECHO sites (P=0.57). Serious adverse events occurred in 13.7% of the patients at the UNM HCV clinic and in 6.9% of the patients at ECHO sites. CONCLUSIONS: The results of this study show that the ECHO model is an effective way to treat HCV infection in underserved communities. Implementation of this model would allow other states and nations to treat a greater number of patients infected with HCV than they are currently able to treat. (Funded by the Agency for Healthcare Research and Quality and others.).

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Metadata

Authors
Arora, S., Thornton, K., Murata, G., Deming, P., Kalishman, S., Dion, D., Parish, B., Burke, T., Pak, W., Dunkelberg, J., Kistin, M., Brown, J., Jenkusky, S., Komaromy, M., & Qualls, C.
Venue
New England Journal of Medicine
Published
2011-06-09
Volume
364
Issue
23
Pages
2199-2207
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
OpenAlex
W2170956924
Cited by
1,076
References
21
FWCI
25.00
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Outcomes of Treatment for Hepatitis C Virus Infection by Primary Care Providers. https://app.cochat.ai/papers/10.1056/nejmoa1009370
The paper
Arora, S., Thornton, K., Murata, G., Deming, P., Kalishman, S., Dion, D., Parish, B., Burke, T., Pak, W., Dunkelberg, J., Kistin, M., Brown, J., Jenkusky, S., Komaromy, M., & Qualls, C. (2011). Outcomes of Treatment for Hepatitis C Virus Infection by Primary Care Providers. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1009370

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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