The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Prasugrel versus Clopidogrel for Acute Coronary Syndromes without Revascularization
Open accessAbstract
BACKGROUND: The effect of intensified platelet inhibition for patients with unstable angina or myocardial infarction without ST-segment elevation who do not undergo revascularization has not been delineated. METHODS: In this double-blind, randomized trial, in a primary analysis involving 7243 patients under the age of 75 years receiving aspirin, we evaluated up to 30 months of treatment with prasugrel (10 mg daily) versus clopidogrel (75 mg daily). In a secondary analysis involving 2083 patients 75 years of age or older, we evaluated 5 mg of prasugrel versus 75 mg of clopidogrel. RESULTS: At a median follow-up of 17 months, the primary end point of death from cardiovascular causes, myocardial infarction, or stroke among patients under the age of 75 years occurred in 13.9% of the prasugrel group and 16.0% of the clopidogrel group (hazard ratio in the prasugrel group, 0.91; 95% confidence interval [CI], 0.79 to 1.05; P=0.21). Similar results were observed in the overall population. The prespecified analysis of multiple recurrent ischemic events (all components of the primary end point) suggested a lower risk for prasugrel among patients under the age of 75 years (hazard ratio, 0.85; 95% CI, 0.72 to 1.00; P=0.04). Rates of severe and intracranial bleeding were similar in the two groups in all age groups. There was no significant between-group difference in the frequency of nonhemorrhagic serious adverse events, except for a higher frequency of heart failure in the clopidogrel group. CONCLUSIONS: Among patients with unstable angina or myocardial infarction without ST-segment elevation, prasugrel did not significantly reduce the frequency of the primary end point, as compared with clopidogrel, and similar risks of bleeding were observed. (Funded by Eli Lilly and Daiichi Sankyo; TRILOGY ACS ClinicalTrials.gov number, NCT00699998.).
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In addition to their initial events, such patients are at substantial risk for recurrent, potentially fatal events.”
From Effects of Icosapent Ethyl on Total Ischemic Events (2019) · cites this paper as [5]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
Wallentin, L., Becker, R. C., Budaj, A., Cannon, C. P., Emanuelsson, H., Held, C., Horrow, J., Husted, S., James, S., Katus, H., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0904327 · Cited by 7,117
Prasugrel versus clopidogrel in patients with acute coronary syndromes
Wiviott, S. D., Braunwald, E., McCabe, C. H., Montalescot, G., Ruzyllo, W., Gottlieb, S., Neumann, F.-J., Ardissino, D., De Servi, S., Murphy, S. A., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa0706482 · Cited by 6,790
Self-citationCox’s regression model for counting processes: A large sample study
Andersen, P. K., & Gill, R. D. (1982) · The Annals of Statistics · doi:10.1214/aos/1176345976 · Cited by 4,419
A Prospective Natural-History Study of Coronary Atherosclerosis
Stone, G. W., Maehara, A., Lansky, A. J., Bruyne, B. D., Cristea, E., Mintz, G. S., Mehran, R., McPherson, J., Farhat, N. Z., Marso, S. P., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1002358 · Cited by 3,301
Authors Task Force Members, Hamm, C. W., Bassand, J., Agewall, S., Bax, J. J., Boersma, E. H., Bueno, H., Caso, P., Dudek, D., Gielen, S., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr236 · Cited by 3,096
Self-citationClopidogrel for Coronary Stenting
Gurbel, P. A., Bliden, K. P., Hiatt, B. L., & O’Connor, C. M. (2003) · Circulation · doi:10.1161/01.cir.0000072771.11429.83 · Cited by 1,544
Self-citationHamm, C. W., Bassand, J., Agewall, S., Bax, J. J., Boersma, E. H., Bueno, H., Caso, P., Dudek, D., Gielen, S., Huber, K., et al. (2012) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2011.11.006 · Cited by 1,062
Self-citationThrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes
Tricoci, P., Huang, Z., Held, C., Moliterno, D. J., Armstrong, P. W., de Werf, F. V., White, H. D., Aylward, P. E., Wallentin, L. C., Chen, E., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1109719 · Cited by 756
Self-citationWright, R. S., Anderson, J. L., Adams, C. D., Bridges, C. R., Casey, D. E., Ettinger, S. M., Fesmire, F. M., Ganiats, T. G., Jneid, H. M., Lincoff, A. M., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.02.011 · Cited by 513
Roe, M. T., Messenger, J. C., Weintraub, W. S., Cannon, C. P., Fonarow, G. C., Dai, D., Chen, A. Y., Klein, L. W., Masoudi, F. A., McKay, C. R., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.05.008 · Cited by 447
Self-citation
Cited by
Sorted by citations
Items 801–873 of 873
Kruger, P. C. (2019) · UWA Profiles and Research Repository (University of Western Australia) · doi:10.26182/5e8a796c6e24c
Review of Antiplatelet Therapy for the Management of Acute Coronary Syndromes
Shivu, G. N. (2016) · Journal of Medical Sciences and Health · doi:10.46347/jmsh.2016.v02i03.007
Prasugrel in the Treatment of Acute Coronary Syndrome
Spartalis, Μ., Tzatzaki, E., Spartalis, E. D., Paschou, S. Α., Athanasiou, A., Iliopoulos, D., Siasos, G., & Voudris, V. A. (2020) · Future Cardiology · doi:10.2217/fca-2020-0018
(2016) · Dental Abstracts · doi:10.1016/j.denabs.2016.07.050
Principales medicamentos antiagregantes: manejo, vigilancia y gestión de las complicaciones
Laine, M., Frère, C., & Bonello, L. (2020) · EMC - Tratado de Medicina · doi:10.1016/s1636-5410(20)44019-x
Benefits of clopidogrel in clinical practice: current data
Кочетков, А. И., Ostroumova, O. D., Kirichenko, A. A., & Aleshkovich, E. (2020) · Russian Journal of Cardiology and Cardiovascular Surgery · doi:10.17116/kardio202013041322
Long term antithrombotic threapy after myocardial infarction: why, to whom and which one?
Varvařovský, I. (2020) · Vnitřní lékařství · doi:10.36290/vnl.2020.045
Luo, L., Pang, Z., Fu, M., Li, Y., Tu, L., & Xu, X. (2020) · Chinese Medical Journal · doi:10.1097/cm9.0000000000001119
Antithrombotic therapy in acute coronary syndrome: undertreatment of elderly?
Muraca, I., Ciatti, F., Migliorini, A., Marchionni, N., & Valenti, R. (2020) · Monaldi Archives for Chest Disease · doi:10.4081/monaldi.2020.1261
Long-term Antithrombotic Therapy for Large and Small Artery Occlusive Disease
Hankey, G. J. (2020) · Cambridge University Press eBooks · doi:10.1017/9781316286234.020
Platelet physiology and pharmacology—relevant considerations for patient care
Lee, C. H., & Angiolillo, D. J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820536-5.00005-7
Fibrinolytic, antiplatelet, and anticoagulant drugs in acute coronary syndromes
Halvorsen, S., Gargiulo, G., Valgimigli, M., & Huber, K. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780198849346.003.0040
Self-citationOstojić, Z. (2021) · Cardiologia Croatica · doi:10.15836/ccar2021.269
Akutes Koronarsyndrom und antithrombozytäre Therapie: Prähospitale Phase: nichts, ASS oder...?
Bauer, T., & Hamm, C. W. (2014) · Herz
Self-citationTicagrelor in Acute Coronary Syndromes
Howard, C. (2015) · doi:10.26686/wgtn.17014211
Non‐ST‐Segment Elevation Acute Coronary Syndrome
Hanna, E. B. (2022) · Wiley eBooks · doi:10.1002/9781119832737.ch1
Shalnev, V. I., Petrova, N. V., & Lukianova, I. Y. (2022) · EMERGENCY MEDICAL CARE · doi:10.24884/2072-6716-2021-22-4-4-11
Basics of Antiplatelet and Anticoagulant Therapy for Cardiovascular Disease
Capranzano, P., & Angiolillo, D. J. (2022) · Interventional Cardiology · doi:10.1002/9781119697367.ch38
PCI Strategies in Acute Coronary Syndromes without ST Segment Elevation (NSTE‐ACS)
Roumeliotis, A., & Brilakis, E. S. (2022) · Interventional Cardiology · doi:10.1002/9781119697367.ch12
Unstable Angina and Non-ST Elevation Myocardial Infarction
Robbins, J., & Gelfand, E. V. (2018) · Contemporary cardiology · doi:10.1007/978-3-319-97622-8_11
Strategia di gestione delle sindromi coronariche acute
Wiel, É., Assez, N., & Goldstein, P. (2020) · EMC - Urgenze · doi:10.1016/s1286-9341(20)43750-0
Principles of Primary and Secondary Prevention of Cardiovascular Disease
Eapen, D. J., Ghasemzadeh, N., Bellam, N., Bhatia, N. K., Valiani, K., Shen, J., VanDam, R. J., Flueckiger, P., Molloy, D. L., Kay, J., et al. (2014) · Springer eBooks · doi:10.1007/978-3-642-37393-0_53-1
Non-ST-Elevation Myocardial Infarction: Management
Cimci, M., Gencer, B. G., & Roffi, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99747-3
Non-ST-segment elevation acute coronary syndromes
Bueno, H., & Barrabés, J. A. (2021) · Oxford University Press eBooks · doi:10.1093/med/9780198849346.003.0042
Medical Management of Coronary Artery Disease
Farag, A., & Zamvar, D. (2014) · Springer eBooks · doi:10.1007/978-3-642-37393-0_234-1
KHAN, M. G. (2014) · Contemporary cardiology · doi:10.1007/978-1-61779-962-4_24
Varenhorst, C., Oskarsson, A., & James, S. K. (2014) · doi:10.1002/9781118493984.ch20
Viruel, M., Muñoz, F., Garmendia, C. M., Parrilla, L., Ruano, C., Rivero, M., Zaidel, E. J., Lalor, N., Pérez, G., & Costabel, J. P. (2022) · Revista Argentina de Cardiología · doi:10.7775/rac.es.v90.i2.20506
Best Practices in Pharmacotherapy for Acute Coronary Syndromes
Barcelona, R. (2022) · US Cardiology Review · doi:10.15420/usc.2022.05
Antiplatelet Therapy in Patients with Acute Coronary Syndrome: An Update
Bashar, A., Hoque, M. H., Chowdhury, M. T., Hasan, A. I., & Ahmed, K. (2020) · University Heart Journal · doi:10.3329/uhj.v17i1.50884
Wang, Y., Geng, Y., Zhang, O., Xu, Q., Xue, Y., Zhou, B., & Zhang, P. (2022) · Research Square · doi:10.21203/rs.3.rs-2290839/v1
Acute Coronary Syndrome in the Older Adult Populations
Rout, A., Hussain, S., & Damluji, A. A. (2023) · Contemporary cardiology · doi:10.1007/978-3-031-16594-8_10
Adawi, N., Rotshild, V., Yanko, S., Mowaswes, M., Amir, O., Haitner, G., Matok, I., & Raccah, B. H. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.1016390
Wang, Y., Geng, Y., Zhang, O., Xu, Q., Xue, Y., Zhou, B., Zhang, P., the CCC-ACS Investigators, Li, A., Li, B., et al. (2023) · European journal of medical research · doi:10.1186/s40001-023-01025-6
Schwartz, G. G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-88286-6.00036-4
Chiarito, M., Cao, D., Sartori, S., Zhang, Z., Vogel, B., Spirito, A., Smith, K. F., Weintraub, W. S., Strauss, C., Toma, C., et al. (2023) · European Heart Journal Acute Cardiovascular Care · doi:10.1093/ehjacc/zuad083
Antithrombotic Therapy in Chronic Kidney Disease
Achim, C. A., Florescu, D.-G., Ditu, B.-M., Voicu-Titere, C., Moisa, R.-V., & Ismail, G. (2023) · Internal Medicine · doi:10.2478/inmed-2023-0249
Parker, W. A., Caterina, R. D., Moliterno, D. J., Kristensen, S. D., & Storey, R. F. (2023) · doi:10.1093/med/9780192869227.003.0016
Pareek, M., & Bhatt, D. L. (2023) · Oxford University Press eBooks · doi:10.1093/med/9780192869227.003.0006
Self-citationGeneral Considerations for Neurointerventional Procedures
Harrigan, M. R., & Deveikis, J. P. (2023) · Contemporary medical imaging · doi:10.1007/978-3-031-45598-8_4
Time-Stretch Imaging toward Auxiliary Diagnosis of COVID-19
周, 雨., 菅野, 寛., 肖, 廷., シャクマトフ, 理., 伊林, 侑., 西川, 真., 矢冨, 裕., & Goda, K. (2021) · The Review of Laser Engineering · doi:10.2184/lsj.49.4_228
Pharmacotherapy in the Modern Interventional Suite
Jneid, H. M. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-26219-4.00004-9
Clinical Follow-Up of Patients after Coronary Artery Bypass Grafting
Oliveira, J. C. (2024) · Cardiology and cardiovascular medicine. · doi:10.5772/intechopen.113939
Pharmacotherapeutic options for coronary thrombosis treatment: where are we today?
Rahman, M., Wedagedera, V., Parker, W. A., & Storey, R. F. (2025) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2025.2450353 · Cited by 1
Barker, N. A., Lisi, D., & Robbins, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-77335-8_10
Antithrombotische Therapie bei polyvaskulärer Atherosklerose
Espinola–Klein, C. (2025) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/a-2359-4422
Defining Chronic Myocyte Injury With hs-cTnT
Miller, G., Davies, S. L., Hatherley, J. D., Lambert, A., Fearon, H., Bailey, L. M., Collinson, P. O., & Khand, A. U. (2025) · JACC Case Reports · doi:10.1016/j.jaccas.2025.103631
Hamza, M., Karamat, M., Harmouch, K. M., Alamzaib, S. M., Jabeen, S., Basit, J., Bhanushali, K. B., Ved, R., Rashdi, A., Almani, M. U., et al. (2025) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-025-07747-5
Radunović, A., Ilić, I., Matic, M., Ostojic, M., Kojić, D., Goločevac, A., Lazarević, N., Mandić, A., Tomovic, M., & Otašević, P. (2025) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd12090362
Clinical Pharmacology of P2Y12 Receptor Inhibitors
Laudani, C., Capodanno, D., & Angiolillo, D. J. (2025) · Springer eBooks · doi:10.1007/978-3-031-96360-5_2
Deurvorst, S. E., El-Hage, E. M. E., van Wingerden, N., Ziesemer, K. A., Sikkens, J. J., & Smulders, Y. M. (2025) · European Heart Journal - Quality of Care and Clinical Outcomes · doi:10.1093/ehjqcco/qcaf128
Tarantini, G., Mojoli, M., Varbella, F., Caporale, R., Rigattieri, S., Andò, G., Cirillo, P., Pierini, S., Santarelli, A., Sganzerla, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13285151
Tarantini, G., Mojoli, M., Varbella, F., Caporale, R., Rigattieri, S., Andò, G., Cirillo, P., Pierini, S., Santarelli, A., Sganzerla, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13285154
Tarantini, G., Mojoli, M., Varbella, F., Caporale, R., Rigattieri, S., Andò, G., Cirillo, P., Pierini, S., Santarelli, A., Sganzerla, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13285148
Wang, Y., Geng, Y., Zhang, O., Xu, Q., Xue, Y., Zhou, B., & Zhang, P. (2023) · Figshare · doi:10.6084/m9.figshare.22603000
Tarantini, G., Mojoli, M., Varbella, F., Caporale, R., Rigattieri, S., Andò, G., Cirillo, P., Pierini, S., Santarelli, A., Sganzerla, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13285142
Tarantini, G., Mojoli, M., Varbella, F., Caporale, R., Rigattieri, S., Andò, G., Cirillo, P., Pierini, S., Santarelli, A., Sganzerla, P., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13285139
Effect of Antithrombotic Therapy on Coronary Heart Disease Risk in People With Diabetes Mellitus
O’Donoghue, M., & Bhatt, D. L. (2026) · Elsevier eBooks · doi:10.1016/b978-0-323-87862-3.00020-3
Self-citationUnstable Angina: Presentation, Diagnosis, and Management
Bostrom, J., & Awtry, E. H. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-15734-9.00049-2
Role of GPVI/Fibrinogen interplay in platelet activation, thrombus formation and stability
Ahmed, M. U. (2020) · theses.fr (ABES) · doi:10.70675/41d4d396za4a6z449dzae65zf98781b379bb
Ibrahim, M. H., Lee, B., McGrath, J., Hess, M., Niemann, D., Aagaard‐Kienitz, B., Ahmed, A. S., & McGuire, L. S. (2026) · Journal of NeuroInterventional Surgery · doi:10.1136/jnis-2026-025144
Low-dose prasugrel-based antiplatelet therapy in patients with coronary artery disease
Jang, A. Y. (2026) · Cardiovascular Prevention and Pharmacotherapy · doi:10.36011/cpp.2026.8.e5
Marquis‐Gravel, G., & Gagnon, C. (2026) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2026.06.002
Hiruma, Y., Watanabe, A., Aikawa, T., Iwagami, M., Slipczuk, L. N., Wiley, J., Briasoulis, Α., Secemsky, E. A., Laham, R. J., & Kuno, T. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.125.047301
Prasugrel vs. Ticagrelor: Can TUXEDO-2 Settle the Debate?
Prezzavento, R., & Capodanno, D. (2026) · Thrombosis and Haemostasis · doi:10.1055/a-2901-6693
Prasugrel: Reassessing Its Role in Contemporary Antiplatelet Therapy
Kamisah, Y., & Hassan, H. H. C. (2026) · Cardiovascular Therapeutics · doi:10.1155/cdr/5538781
Kutcher, S., Dendukuri, N., Dandona, S., & Brophy, J. M. (2026) · medRxiv · doi:10.64898/2026.08.31.26361847
Prasugrel in the management of acute coronary syndromes: a systematic review
Akman, C., Ucar, A., Ünaldı, M., KILIÇ, G., ERDEM, B., Vargun, P., Şahin, Ş., Özkaya, B., & Karcıoğlu, Ö. (2026) · DARU Journal of Pharmaceutical Sciences · doi:10.1007/s40199-026-00636-8
Prasugrel 5 mg in acute coronary syndromes: indications and clinical outcomes
Tanajura, L. F., Delamain, J. H. H., Labrunie, A., de Souza, G. B. N., & Tanajura, L. G. D. O. (2026) · Revista da Associação Médica Brasileira · doi:10.1590/1806-9282.20260528
Akutes Koronarsyndrom (außer STEMI)
Schulz, E., & Münzel, T. F. (2015) · Springer eBooks · doi:10.1007/978-3-642-54676-1_191-1
Metadata
- Authors
- Roe, M. T., Armstrong, P. W., Fox, K. A. A., White, H. D., Prabhakaran, D., Goodman, S. G., Cornel, J. H., Bhatt, D. L., Clemmensen, P., Martinez, F., Ardissino, D., Nicolau, J. C., Boden, W. E., Gurbel, P. A., Ruzyllo, W., Dalby, A. J., McGuire, D. K., Leiva-Pons, J. L., Parkhomenko, A., Gottlieb, S., Topacio, G. O., Hamm, C., Pavlides, G., Goudev, A. R., Oto, A., Tseng, C.-D., Merkely, B., Gasparovic, V., Corbalan, R., Cinteză, M., McLendon, R. C., Winters, K. J., Brown, E. B., Lokhnygina, Y., Aylward, P. E., Huber, K., Hochman, J. S., & Ohman, E. M.
- Affiliations
- Duke Medical Center (US)
- University of Alberta (CA)
- Duke University (US)
- St. Michael's Hospital (CA)
- Brigham and Women's Hospital (US)
- University of Copenhagen (DK)
- National Taiwan University (TW)
- Eli Lilly (United States) (US)
- Flinders University (AU)
- ORCID
- Roe, Matthew T.
- Armstrong, Paul W.
- Fox, Keith A.A.
- White, Harvey D.
- Prabhakaran, Dorairaj
- Goodman, Shaun G.
- Cornel, Jan H.
- Bhatt, Deepak L.
- Clemmensen, Peter
- Ardissino, Diego
- Boden, William E.
- Gurbel, Paul A.
- McGuire, Darren K.
- Leiva-Pons, Jose L.
- Parkhomenko, Alexander
- Gottlieb, Shmuel
- Hamm, Christian
- Goudev, Assen R.
- Oto, Ali
- Aylward, Philip E.
- Huber, Kurt
- Hochman, Judith S.
- Ohman, E. Magnus
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2012-10-04
- Volume
- 367
- Issue
- 14
- Pages
- 1297-1309
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2109577952
- Cited by
- 874
- References
- 18
- Citations by year
- 2026: 16 · 2025: 24 · 2024: 14 · 2023: 31 · 2022: 43 · 2021: 49 · 2020: 58 · 2019: 53 · 2018: 70 · 2017: 92 · 2016: 71 · 2015: 91 · 2014: 114 · 2013: 124 · 2012: 20
- FWCI
- 71.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (publishedVersion)
- Scientific Electronic Library Online (São Paulo Research Foundation, Latin American and Caribbean Center on Health Sciences Information, Conselho Nacional de Desenvolvimento Científico e Tecnológico) (publishedVersion)
- Trakya University's Institutional Open Access System (Trakya University) (submittedVersion, other-oa)
- Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli" (submittedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- Hacettepe University Institutional Repository (hacettepe.edu.tr) (submittedVersion, other-oa)
- ORBi (University of Liège) (submittedVersion)
- Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Funders
- Abbott Laboratories
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Amylin Pharmaceuticals
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Gilead Sciences
- Helsinn
- Boston Scientific Corporation
- Boston VA Research Institute
- Regeneron Pharmaceuticals
- Amarin Corporation
- Medicines Company
- Regado Biosciences
- Eisai
- Astellas Pharma
- Servier
- Genentech
- Janssen Pharmaceuticals
- Daiichi Sankyo Europe
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Antiplatelet Therapy and Cardiovascular Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Coronary Interventions and Diagnostics
- Keywords
- prasugrel, clopidogrel, acute coronary syndrome, non-ST-elevation myocardial infarction, unstable angina, platelet aggregation inhibition, antiplatelet therapy, bleeding risk, heart failure, cardiovascular mortality, stroke, elderly patients
- MeSH terms
- Prasugrel Hydrochloride, Clopidogrel, Aged, Angina, Unstable, Aspirin, Cardiovascular Diseases, Double-Blind Method, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Male, Middle Aged, Myocardial Infarction, Piperazines, Platelet Aggregation Inhibitors, Thiophenes, Ticlopidine, Stroke, Kaplan-Meier Estimate, Acute Coronary Syndrome, Purinergic P2 Receptor Antagonists
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review