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Cited by 769

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Intravascular Complications of Central Venous Catheterization by Insertion Site

Open access
Parienti, Jean-Jacques, Mongardon, Nicolas, Mégarbane, Bruno, Mira, Jean-Paul, Kalfon, Pierre, Gros, Antoine, Marqué, Sophie, Thuong, Marie, Pottier, Véronique, Ramakers, Michel, Savary, Benoît, Seguin, Amélie, Valette, Xavier, Terzi, Nicolas, Sauneuf, Bertrand, Cattoir, Vincent, Mermel, Leonard A., du Cheyron, Damien·2015·New England Journal of Medicine
DOI 10.1056/nejmoa1500964
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Abstract

BACKGROUND: Three anatomical sites are commonly used to insert central venous catheters, but insertion at each site has the potential for major complications. METHODS: In this multicenter trial, we randomly assigned nontunneled central venous catheterization in patients in the adult intensive care unit (ICU) to the subclavian, jugular, or femoral vein (in a 1:1:1 ratio if all three insertion sites were suitable [three-choice scheme] and in a 1:1 ratio if two sites were suitable [two-choice scheme]). The primary outcome measure was a composite of catheter-related bloodstream infection and symptomatic deep-vein thrombosis. RESULTS: A total of 3471 catheters were inserted in 3027 patients. In the three-choice comparison, there were 8, 20, and 22 primary outcome events in the subclavian, jugular, and femoral groups, respectively (1.5, 3.6, and 4.6 per 1000 catheter-days; P=0.02). In pairwise comparisons, the risk of the primary outcome was significantly higher in the femoral group than in the subclavian group (hazard ratio, 3.5; 95% confidence interval [CI], 1.5 to 7.8; P=0.003) and in the jugular group than in the subclavian group (hazard ratio, 2.1; 95% CI, 1.0 to 4.3; P=0.04), whereas the risk in the femoral group was similar to that in the jugular group (hazard ratio, 1.3; 95% CI, 0.8 to 2.1; P=0.30). In the three-choice comparison, pneumothorax requiring chest-tube insertion occurred in association with 13 (1.5%) of the subclavian-vein insertions and 4 (0.5%) of the jugular-vein insertions. CONCLUSIONS: In this trial, subclavian-vein catheterization was associated with a lower risk of bloodstream infection and symptomatic thrombosis and a higher risk of pneumothorax than jugular-vein or femoral-vein catheterization. (Funded by the Hospital Program for Clinical Research, French Ministry of Health; ClinicalTrials.gov number, NCT01479153.).

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Metadata

Authors
Parienti, J.-J., Mongardon, N., Mégarbane, B., Mira, J.-P., Kalfon, P., Gros, A., Marqué, S., Thuong, M., Pottier, V., Ramakers, M., Savary, B., Seguin, A., Valette, X., Terzi, N., Sauneuf, B., Cattoir, V., Mermel, L. A., & du Cheyron, D.
Venue
New England Journal of Medicine
Publisher
Massachusetts Medical Society
Published
2015-09-24
Volume
373
Issue
13
Pages
1220-1229
ISSN
  • 0028-4793 (ISSN-L)
  • 1533-4406
DOI
10.1056/nejmoa1500964
OpenAlex
W2136111108
Cited by
769
References
30
FWCI
83.53
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Intravascular Complications of Central Venous Catheterization by Insertion Site. https://app.cochat.ai/papers/10.1056/nejmoa1500964
The paper
Parienti, J.-J., Mongardon, N., Mégarbane, B., Mira, J.-P., Kalfon, P., Gros, A., Marqué, S., Thuong, M., Pottier, V., Ramakers, M., Savary, B., Seguin, A., Valette, X., Terzi, N., Sauneuf, B., Cattoir, V., Mermel, L. A., & du Cheyron, D. (2015). Intravascular Complications of Central Venous Catheterization by Insertion Site. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1500964

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.