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Molecular Evidence of Sexual Transmission of Ebola Virus
Open accessAbstract
A suspected case of sexual transmission from a male survivor of Ebola virus disease (EVD) to his female partner (the patient in this report) occurred in Liberia in March 2015. Ebola virus (EBOV) genomes assembled from blood samples from the patient and a semen sample from the survivor were consistent with direct transmission. The genomes shared three substitutions that were absent from all other Western African EBOV sequences and that were distinct from the last documented transmission chain in Liberia before this case. Combined with epidemiologic data, the genomic analysis provides evidence of sexual transmission of EBOV and evidence of the persistence of infective EBOV in semen for 179 days or more after the onset of EVD. (Funded by the Defense Threat Reduction Agency and others.).
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Emergence of Zaire Ebola Virus Disease in Guinea
Baize, S., Pannetier, D., Oestereich, L., Rieger, T., Koivogui, L., Magassouba, N., Soropogui, B., Sow, M. S., Keïta, S., De Clerck, H., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1404505 · Cited by 1,366
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Cited by
Towards a genomics-informed, real-time, global pathogen surveillance system
Gardy, J. L., & Loman, N. J. (2018) · Nature Reviews Genetics · doi:10.1038/nrg.2017.88 · Cited by 771
Late Ebola virus relapse causing meningoencephalitis: a case report
Jacobs, M., Rodger, A., Bell, D. J., Bhagani, S., Cropley, I., Filipe, A., Gifford, R. J., Hopkins, S., Hughes, J., Jabeen, F., et al. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30386-5 · Cited by 361
The evolution of Ebola virus: Insights from the 2013-2016 epidemic
Holmes, E. C., Dudas, G., Rambaut, A., & Andersen, K. G. (2016) · Nature · doi:10.1038/nature19790 · Cited by 314
Metadata
- Authors
- Mate, S. E., Kugelman, J. R., Nyenswah, T. G., Ladner, J. T., Wiley, M. R., Cordier-Lassalle, T., Christie, A., Schroth, G. P., Gross, S. M., Davies-Wayne, G. J., Shinde, S. A., Murugan, R., Sieh, S. B., Badio, M., Fakoli, L., Taweh, F., de Wit, E., van Doremalen, N., Munster, V. J., Pettitt, J., Prieto, K., Humrighouse, B. W., Ströher, U., DiClaro, J. W., Hensley, L. E., Schoepp, R. J., Safronetz, D., Fair, J., Kuhn, J. H., Blackley, D. J., Laney, A. S., Williams, D. E., Lo, T., Gasasira, A., Nichol, S. T., Formenty, P., Kateh, F. N., De Cock, K. M., Bolay, F., Sanchez-Lockhart, M., & Palacios, G.
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 2015-12-17
- Volume
- 373
- Issue
- 25
- Pages
- 2448-2454
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2314681741
- Cited by
- 434
- References
- 1
- FWCI
- 50.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Molecular Evidence of Sexual Transmission of Ebola Virus. https://app.cochat.ai/papers/10.1056/nejmoa1509773
- The paper
- Mate, S. E., Kugelman, J. R., Nyenswah, T. G., Ladner, J. T., Wiley, M. R., Cordier-Lassalle, T., Christie, A., Schroth, G. P., Gross, S. M., Davies-Wayne, G. J., Shinde, S. A., Murugan, R., Sieh, S. B., Badio, M., Fakoli, L., Taweh, F., de Wit, E., van Doremalen, N., Munster, V. J., . . . Palacios, G. (2015). Molecular Evidence of Sexual Transmission of Ebola Virus. New England Journal of Medicine. https://doi.org/10.1056/nejmoa1509773
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
